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Senior Accounting Manager

Asimov
Boston, MA Full Time
POSTED ON 11/20/2025 CLOSED ON 12/24/2025

What are the responsibilities and job description for the Senior Accounting Manager position at Asimov?

Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics.

We are seeking a strategic and hands-on Senior Accounting Manager to establish and lead our accounting operations. In this newly created role, and reporting to the Head of Commercial, you will be responsible for ensuring accurate revenue recognition, supporting budgeting and forecasting, streamlining and implementing processes, while overseeing all accounts payable and receivable activities.

This role offers the unique opportunity to design and optimize financial systems from the ground up within a rapidly growing biotech startup. The ideal candidate will thrive in a collaborative, science-driven environment while bringing financial rigor, process discipline, and forward-thinking leadership to drive innovation and fuel the company’s next phase of growth.

About The Role

  • Accounting & Controls: Ensure timely and accurate recording of revenue, COGS, and expenses across all product lines. Maintain reconciliations, accruals, and closing schedules.
  • Audit & Compliance: Lead preparation for the annual audit, liaise with auditors on technical issues (e.g., revenue recognition, asset classification), and ensure compliance with tax and regulatory requirements.
  • Budget Tracking: Monitor spend against budget, provide variance analyses, and maintain rolling forecasts with input from department leads.
  • Systems & Processes: Recommend and implement scalable general ledger and procurement systems (e.g., Prendio or equivalents) to improve reporting, visibility, and spend control.
  • Cash & Runway Visibility: Produce monthly cash flow reports, identify risks to runway, and flag required actions.
  • Reporting: Prepare accurate and timely monthly/quarterly financial statements, management reports, and supporting schedules for leadership and investors.
  • Payroll: Manage scalable payroll systems and processes, ensuring accuracy, timeliness, and compliance across multiple states, while partnering with HR to support an expanding and distributed workforce.

About You

  • You have a Bachelor’s or Master’s degree in Accounting or Finance with 7 years of progressive experience in accounting/finance. CPA certification is strongly preferred.
  • You ideally have prior life sciences, biotech, or high-growth tools/services experience.
  • You have strong technical accounting expertise, including revenue recognition, COGS tracking, accruals, and GAAP compliance.
  • You have experience with audits, tax compliance, and working directly with external auditors.
  • You are proficient with general ledger systems, procurement platforms, and financial reporting tools.
  • You’ve demonstrated the ability to build scalable accounting processes and internal controls in a high-growth company.
  • You have an analytical mindset with attention to detail; able to identify variances, trends, and risks early.
  • You have excellent communication skills, able to translate accounting into clear business insights.

We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.

Compensation Range: $140K - $150K

Salary : $140,000 - $150,000

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