Job Title: Enterprise Architect (Business Technology Architect) – Life Sciences Industry

Location: San Francisco, CA | Chicago, IL | Houston, TX | Dallas, TX | Atlanta, GA | New York City, NY (Onsite)
Employment Type: Full-Time (Direct Hire)

Role Overview

We are seeking a senior Enterprise Architect with deep expertise in Life Sciences to define and drive end-to-end business and technology architecture across regulated, data-driven environments. This role will shape enterprise-wide technology strategy across R&D, Clinical, Manufacturing, Supply Chain, Regulatory, Quality, and Commercial domains, ensuring scalable, compliant, and high-performing digital ecosystems.

The architect will act as a strategic advisor to executive leadership, translating business priorities into robust architecture blueprints and enabling modern, cloud-enabled, and data-driven Life Sciences platforms.

Key Responsibilities

Enterprise Architecture Leadership

• Define and manage enterprise-wide architecture strategy, including target state models, capability roadmaps, and reference architectures for Life Sciences organizations
• Lead architecture governance and ensure alignment with business outcomes, regulatory requirements, and long-term enterprise goals
• Drive adoption of architecture standards across business and technology teams in a complex, matrixed environment

Business & Technology Alignment

• Translate business objectives such as regulatory compliance, product quality, operational efficiency, and time-to-market into architectural requirements
• Align enterprise capabilities with business processes, services, platforms, and operating models
• Ensure architecture decisions support scalability, resilience, security, and observability across systems

Life Sciences Domain Architecture

• Architect integrated ecosystems across regulated Life Sciences functions including:
  • R&D and Clinical Operations
  • Regulatory Affairs and Pharmacovigilance/Safety
  • Manufacturing and Supply Chain
  • Quality Management and Commercial Operations
• Support industry segments including Pharmaceuticals, Biotechnology, MedTech, Diagnostics, and Consumer Health
• Work across partner ecosystems including CROs, CMOs/CDMOs, and distributors

Platform & Application Architecture

• Design and guide architecture for enterprise platforms such as:
  • ERP systems
  • LIMS, MES, QMS, CTMS
  • CRM and regulatory systems
  • Manufacturing and supply chain platforms
• Balance packaged solutions vs. custom development, ensuring sustainability and upgrade readiness
• Define integration strategies across enterprise systems and third-party applications

Integration & Data Architecture

• Define enterprise integration strategies including API-first, event-driven, and microservices-based architectures
• Establish data architecture standards covering MDM, data governance, identity, and observability
• Enable secure and governed data flows across R&D, clinical, manufacturing, and commercial domains
• Support AI/ML and GenAI use cases with proper data controls and architecture foundations

Cloud, AI & Modern Architecture

• Design hybrid and cloud-native architectures across AWS, Azure, and Google Cloud Platform
• Evaluate and adopt emerging technologies such as AI, GenAI, automation, and intelligent document processing
• Enable scalable digital platforms using microservices, event streaming, and modern engineering practices

Operational Excellence & Reliability

• Define non-functional requirements including availability, latency, scalability, and resiliency for regulated environments
• Ensure architecture supports operational realities such as batch processing, global manufacturing, and regulatory submissions
• Strengthen system reliability, performance, and compliance across enterprise platforms

Stakeholder Engagement & Advisory

• Act as a trusted advisor to CIO, CTO, and business leadership teams
• Translate architectural decisions into clear business outcomes, risks, and trade-offs
• Lead cross-functional architecture discussions across multiple workstreams and business units
• Influence senior stakeholders and drive alignment on enterprise technology strategy

Required Skills & Experience

• Bachelor’s degree in Computer Science, Engineering, Information Systems, or equivalent experience
• 12 years of experience in Enterprise or Solution Architecture roles
• Strong experience in regulated industries (preferably Life Sciences) or complex enterprise environments
• Proven expertise in architecting package-based and hybrid enterprise systems
• Deep understanding of:
  • Cloud platforms (AWS, Azure, Google Cloud Platform)
  • APIs, microservices, event-driven architecture
  • Data architecture, governance, and integration patterns
• Experience defining enterprise architecture frameworks, standards, and roadmaps
• Strong leadership experience managing architecture teams or large cross-functional initiatives
• Familiarity with AI-assisted tools (e.g., Copilot-style platforms) for architecture acceleration
• Excellent executive communication and stakeholder management skills
• Ability to influence decision-making in large, complex organizations