Sr Research Scientist - Biochemistry

We are seeking a Sr Research Scientist specializing in Biochemistry to design, develop, and execute various biochemical and biophysical assays. This role involves supporting hit identification, validation, and mechanistic studies of various modalities, including inhibitors, activators, and degraders. The ideal candidate will have significant hands-on experience in laboratory settings and expertise in enzymology, biochemical assays, and biophysics.

Responsibilities

• Design, develop, and execute biochemical and biophysical assays to support hit identification, validation, and mechanistic studies.
• Troubleshoot assay performance issues by analyzing assay variability and optimizing protocols for robustness and reproducibility.
• Perform high-throughput screening and related assays to evaluate compound libraries, assessing affinity, specificity, and binding kinetics.
• Analyze and interpret experimental data using statistical software, presenting findings in reports and discussions.
• Support protein expression and purification workflows to generate high-quality proteins for assays.
• Operate and maintain lab instrumentation including multimode plate readers and automated liquid handlers.
• Maintain accurate and timely electronic lab notebooks and contribute to technical documentation.

• Fundamental understanding of enzymology, biochemical assays, and biophysics.
• Experience in basic biochemistry lab work, including buffer preparation, reagent generation, and assay development.
• Hands-on experience with protein purification and characterization.
• Proficiency in data analysis and curve-fitting software such as Prism and Genedata.

• Demonstrated experience working collaboratively across various disciplines.
• Flexibility to adjust priorities to meet project goals.
• Ability to work independently or as part of a team.
• Highly organized with strong analytical, documentation, time management, and multitasking skills.
• Bachelor’s, Master’s, or Ph.D. degree in Chemistry, Biochemistry, Biophysics, Chemical Biology, or a related field.

This position is onsite and functions well in a fast-paced setting, offering the opportunity to work in a vibrant research environment.

Job Type & Location

This is a Contract position based out of Wilmington, DE.

The pay range for this position is $40.00 - $41.00/hr.

Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following:
• Medical, dental & vision
• Critical Illness, Accident, and Hospital
• 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available
• Life Insurance (Voluntary Life & AD&D for the employee and dependents)
• Short and long-term disability
• Health Spending Account (HSA)
• Transportation benefits
• Employee Assistance Program
• Time Off/Leave (PTO, Vacation or Sick Leave)

This is a fully onsite position in Wilmington,DE.

This position is anticipated to close on Jun 13, 2026.

About Actalent

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email actalentaccommodation@actalentservices.com for other accommodation options.

San Francisco Fair Chance Ordinance: Pursuant to the San Francisco Fair Chance Ordinance, for all positions located in the city and county of San Francisco, we will consider for employment qualified applicants with arrest and conviction records.

Massachusetts Lie Detector: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Use of Artificial Intelligence (AI): We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing, screening, and evaluating candidates. AI helps assess applications and qualifications, but final decisions are made by our hiring team. By applying, you acknowledge and agree that your application may be reviewed using AI tools.

Salary : $40 - $41