LCMS Method Development Scientist

We are seeking a dedicated LCMS Method Development Scientist III to join our Bioanalytical Team. In this role, you will lead method development for a variety of molecules across different species and matrices, acting as the scientific lead for troubleshooting and supporting other groups. You will also serve as a scientific expert to the broader business. This position plays a key role in designing and conducting complex studies to generate high-quality scientific results and developing new strategies, techniques, and instrumentation for bioanalytical chemistry.

• Start routine analyses on LCMS systems independently while ensuring compliance with applicable methods, protocols, SOPs, and regulatory guidelines.
• Conduct complex and challenging feasibility and development studies.
• Implement new techniques and instrumentation to enhance bioanalytical operations.
• Lead troubleshooting efforts and solve challenging bioanalytical problems.
• Evaluate the interest and feasibility of research projects requiring high creativity and technical organization.
• Direct and conduct fundamental and application studies in bioanalytical chemistry.
• Monitor, evaluate, and review the scientific performance of assays.
• Author scientific papers for peer-reviewed journals and present at scientific meetings.
• Engage in scientific mentoring, including training on study-specific techniques and assisting with complex analytical work.
• Contribute to long-range planning and technical policies of the department.
• Perform other related duties as assigned.

• Bachelor's degree in Biology, Chemistry, Clinical Laboratory Science, Medical Technology, or related field.
• Minimum of 5 years of analytical chemistry experience.
• At least 3 months of experience with HPLC and LCMS.
• Expertise in bioanalytical chemistry.
• Proven track record of analytical method development.
• Experience with analytical instrumentation such as HPLC, GC, LC/MS/MS.
• Highly skilled in conducting research, interpreting data, and writing reports.
• Effective oral and written communication skills.

• PhD in analytical chemistry or related field with 1-2 years of related experience, or a Master’s degree with 3-5 years of experience. A Bachelor's degree may be considered with substantial experience.
• Experience in large molecule, oligo, and ADC LC/MS/MS analysis is a plus.
• Proficiency with computers and familiarity with laboratory information systems.
• Knowledge of laboratory automation software, system software, and Microsoft applications.
• Experience in performing scientific presentations and preparing scientific publications.

The position operates on a standard Monday to Friday schedule from 8 AM to 5 PM, based in Indianapolis. Overtime and weekend work may be required. The role involves attending technical conferences and exhibits as necessary. A 9% shift differential will be included once the candidate begins the assignment.

This is a Contract to Hire position based out of Indianapolis, IN.

The pay range for this position is $40.00 - $45.50/hr.

Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following: • Medical, dental & vision • Critical Illness, Accident, and Hospital • 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available • Life Insurance (Voluntary Life & AD&D for the employee and dependents) • Short and long-term disability • Health Spending Account (HSA) • Transportation benefits • Employee Assistance Program • Time Off/Leave (PTO, Vacation or Sick Leave)

This is a fully onsite position in Indianapolis,IN.

This position is anticipated to close on Mar 31, 2026.

Diversity, Equity & Inclusion

At Actalent, diversity and inclusion are a bridge towards the equity and success of our people. DE&I is embedded into our culture through:

• Hiring diverse talent
• Maintaining an inclusive environment through persistent self-reflection
• Building a culture of care, engagement, and recognition with clear outcomes
• Ensuring growth opportunities for our people

Actalent is an equal opportunity employer.

About Actalent

Actalent is a global leader in engineering and sciences services. For more than 40 years, we’ve helped visionary companies advance their goals. Headquartered in the United States, our teams span 150 offices across North America, EMEA, and APAC—with four delivery centers in India led by 1,000 extraordinary employees who connect their passion with purpose every day.

Our Bangalore, Hyderabad, Pune, and Chennai delivery centers are hubs of engineering expertise, with core capabilities in mechanical and electrical engineering, systems and software, and manufacturing engineering. Our teams deliver work across multiple industries including transportation, consumer and industrial products, and life sciences. We serve more than 4,500 clients, including many Fortune 500 brands. Learn more about how we can work together at actalentservices.com.

Salary : $40 - $46