DynamiCure Biotechnology is Hiring a Senior Scientist, In Vitro Pharmacology Near Middlesex, MA
Key Responsibilities And Activities
Design, develop, and execute cell-based bioassays to evaluate performance of investigative drugs (biologics)
Stay updated with cutting edge discoveries and trends and contribute to the company’s R&D strategy to generate and test actionable development plans
Identify emerging methods, tools, and biology approaches, and implement them when applicable
Function as a key team member, and simultaneously train and supervise associates on the R&D team
Collaborate closely with other scientists and research associates on the R&D team
Contribute to work with external parties, including academic collaborators and CROs to create comprehensive capabilities for MoA, target validation and potency studies
Write clear and concise research reports and ensure study documentation and update protocols to ELN
Participate and contribute to internal discussions and meetings
Present results to the project leadership team and management in an organized and timely manner
Required Education, Experience, Skills And Competencies
Ph.D. in Cellular Biology, Immunology, or a relevant discipline
At least 2 years of industry research experience
Extensive experience working with different types of in vitro systems such as immune cells, epithelial cells, fibroblasts, endothelial cells, and other cell lines
Strong background with cell-based assays to interrogate immune pathway activation, immune suppression, cytotoxicity, antibody mediated cell killing
Broad skillset for target validation, potency evaluation and MoA interrogations is highly desired, including the use of tissue culture approach with multiple readouts, flow cytometry, ex-vivo studies, use of gene knockdown tools, conventional immunoassays, phosphorylation analysis and conventional pulldown assays
Hands on ability to execute wet lab experiments, data processing, and ability to effectively communicate key scientific findings across the organization
Ability to establish and maintain cooperative working relationships with co-workers and other stakeholders
Ability to adjust to workload changes and prioritize competing demands
Ability to balance the big picture and fine technical details
Outstanding organizational, critical thinking, and problem-solving skills