Principal Investigator

Location: TEXAS (Hybrid)

Engagement Type: Independent Contractor | Per-Study / As-Needed

Specialties of Interest: Internal Medicine, Family Medicine, Metabolic Disease, Geriatrics, Endocrinology, Cardiology, Infectious Disease, Women’s Health, Pain Management, or Related Fields

About Us

We are building a next-generation clinical trials network that transforms community pharmacies into high-performing clinical trial sites. Our model expands patient access, accelerates enrollment, and enables sponsors to run efficient, decentralized and hybrid trials.

As we activate pharmacy sites nationwide, we are seeking experienced Principal Investigators (PIs) to support study start-up, regulatory submissions, and trial oversight on a non-full-time, per-study basis.

The Opportunity

This role is ideal for physicians who:

• Want to participate in clinical research without full-time site commitments
• Are interested in innovative, pharmacy-embedded trial models
• Prefer flexible, study-based engagement
• PI engagement occurs both during the pre-award submission phase and post-award study execution, with scope and compensation defined per study.

Key Responsibilities

• Serve as Principal Investigator of record for assigned pharmacy-based clinical trials
• Participate in pre-award study activities, including protocol review, feasibility assessments, and initial study applications and regulatory submissions (e.g., IRB, sponsor, FDA as applicable)
• Provide medical and scientific input during sponsor and CRO site selection and feasibility reviews
• Support development and execution of regulatory-ready site documentation prior to trial award
• Oversee trial conduct post-award, ensuring compliance with ICH-GCP, FDA regulations, and sponsor requirements
• Provide ongoing medical oversight and safety supervision throughout the study lifecycle
• Collaborate with pharmacists, study coordinators, sponsors, and CRO partners to ensure protocol adherence and data integrity
• Participate in investigator meetings and study-related reviews (primarily virtual; on-site as needed)
• Contribute to continuous improvement of pharmacy-embedded clinical research workflows

Qualifications

• MD or DO (required)
• Active, unrestricted U.S. medical license
• Prior experience as a Principal Investigator or Sub-Investigator
• Strong knowledge of GCP and clinical trial regulations
• Comfortable working with decentralized / hybrid trial models
• Ability to engage on a per-study, non-full-time basis

What We Offer

• Flexible, per-study compensation
• No full-time site burden
• Opportunity to shape an innovative pharmacy-based clinical trials ecosystem
• Access to a growing pipeline of industry-sponsored and investigator-initiated studies
• Long-term collaboration as our network scales nationally

How to Apply

Interested candidates should submit the details below to: contact@zorarxtrials.com

• CV