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Senior Accountant

xairatherapeutics
South San Francisco, CA Full Time
POSTED ON 3/22/2026 CLOSED ON 4/22/2026

What are the responsibilities and job description for the Senior Accountant position at xairatherapeutics?

About Xaira Therapeutics

Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.

About the Role 

The senior accountant will be reporting to the Corporate Controller and is a key contributor to support accounting operations and prepare other ad hoc analysis as needed. This position will be responsible for performing general accounting, account payables or payroll related tasks, and work with cross-functional teams, support projects, and implement process improvements in a fast-paced environment.


Key Responsibilities

Accounting & Financial Reporting

  • Support and adhere to a monthly close and year-end close schedule by preparing accurate journal entries and completing reconciliation and analyses for various accounts timely.
  • Assist with monthly management financial packages (with analysis) and other management reports as requested (this includes understanding and clearly articulating the financial results of the company and preparing balance sheet, income statement fluctuation)
  • Coordinate with external auditors and provide required audit support.
  • Prepare and support tax PBC request in various area (including federal, state and tax provision for audit requirement)

Payroll & Compliance

  • Process and oversee payroll through PayPro, ensuring accuracy in employee compensation, deductions, benefits, and tax withholdings.
  • Reconcile payroll-related accounts and prepare payroll journal entries.
  • Maintain confidentiality and ensure data integrity in all payroll and employee financial records.

Operational Support

  • Assist account payable operations, including vendor invoices, payment processing, and purchase order reconciliation.
  • Identify opportunities to automate and improve accounting processes using ERP systems or other tools.
  • Work with cross-functional teams across the company to ensure proper support for the business unit.
  • Work on ad-hoc request as needed and directed by management

 

Qualifications

  • Bachelor’s degree in Accounting, Finance, or a related field.
  • Minimum 5 years’ experience in accounting, including at least 2 years in a senior or lead role.
  • Strong understanding of US GAAP
  • Proficiency in NetSuite accounting software.
  • Advanced Excel skills and familiarity with financial analysis tools.
  • Excellent analytic, written, verbal and organizational skills with a proven ability to manage conflicting priorities to deliver a high-quality work product required.
  • Highly self-motivated individual who is disciplined, detail-oriented, and works well under pressure in a fast-paced deadline-oriented environment required.
  • Advanced Excel and Google Suite of products (Sheets, Docs, Slides) is a plus.
  • Biotech/pharmaceutical industry experience preferred

 

Compensation

We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. The base pay range for this position is expected to be $110,000 - $130,000 annually; however, the base pay offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.

Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.

TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes. Please do not forward resumes to our jobs alias or employees. XairaTherapeutics is not responsible for any fees related to unsolicited resumes.

Salary : $110,000 - $130,000

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