Demo

Senior Scientist II - Biophysics

WuXi AppTec
Natick, MA Full Time
POSTED ON 11/21/2025 CLOSED ON 12/17/2025

What are the responsibilities and job description for the Senior Scientist II - Biophysics position at WuXi AppTec?

We are a fast-growing research and services division in WuXi AppTec and are working on developing cutting-edge multidisciplinary drug discovery platforms combining the latest technologies in biology, chemistry, biophysics, engineering, and informatics. We are seeking a highly motivated and collaborative biophysicist to play an integral role in expanding the capabilities at our site in Natick MA. This position is critical to the successful development, implementation and business operations of biophysics platforms and services for the business unit.

Responsibilities

  • Designs and executes novel SPR, TSA, and other biophysics studies, including protein-small molecule interactions, protein-protein interactions, and fragment screening.
  • Analyzes and interprets biophysical data.
  • Works closely with clients to establish assays.
  • Prepares scientific reports and presents scientific data.
  • Develops workflow and processes.
  • Mentors junior scientists in the lab.
  • Works broadly and flexibly with the biophysics business group across different geographic regions.
  • Contribute to troubleshooting, planning, and biophysics strategy as a key member of the biophysics group.
  • Develops and performs orthogonal target engagement, or additional binding assays in line with project requirements.

Qualifications

Experience / Education

  • Bachelor's with 14 years’ experience; Master's with 10 years’ experience, or PhD with 6 years’ experience. Master or PhD degree is preferred in Biochemistry or Biophysics.
  • Industry experience in Pharma/Biotech and/or drug R&D process is preferred.
  • Proven hands-on experience with developing and troubleshooting biophysical assays (SPR, MST, DSF/TSA, GCI, ITC and/or MS).
  • Deep understanding of binding kinetics and rigorous data analysis
  • Demonstrated understanding of complex scientific procedures and technical proficiency with in vitro assays.

Knowledge / Skills / Abilities:

  • Ability to demonstrate scientific creativity, critical thinking and fast learning capabilities.
  • Outstanding written and oral communication skills.
  • Interpersonal skills to seamlessly fit within a teamwork driven environment.
  • Ability to effectively communicate with internal team colleagues and external clients to promote world class service.
  • Must be able to read, write and understand English.

Physical Requirements:

  • Must be able to work in an office environment with minimal noise conditions.
  • Must be able to work in a lab setting with exposure to biohazards, chemicals
  • Must be able to wear appropriate PPE
  • Must be able to work in an environment with variable noise levels
  • Ability to stand/sit/walk for long periods
  • Ability to lift 10 lbs. routinely
  • Ability to crouch, bend, twist, and reach
  • Ability to push/pull 10 lbs. routinely
  • Clarity of Vision

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability

This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. Employees holding this position will be required to perform any other job-related duties as requested by Management.

Salary.com Estimation for Senior Scientist II - Biophysics in Natick, MA
$124,808 to $155,766
If your compensation planning software is too rigid to deploy winning incentive strategies, it’s time to find an adaptable solution. Compensation Planning
Enhance your organization's compensation strategy with salary data sets that HR and team managers can use to pay your staff right. Surveys & Data Sets

What is the career path for a Senior Scientist II - Biophysics?

Sign up to receive alerts about other jobs on the Senior Scientist II - Biophysics career path by checking the boxes next to the positions that interest you.
Income Estimation: 
$116,765 - $144,626
Income Estimation: 
$142,836 - $179,016
Income Estimation: 
$112,363 - $146,135
Income Estimation: 
$153,127 - $203,425
Income Estimation: 
$139,626 - $193,276
Income Estimation: 
$164,650 - $211,440
Income Estimation: 
$130,030 - $173,363
Income Estimation: 
$139,626 - $193,276
Income Estimation: 
$194,895 - $259,743
Income Estimation: 
$192,057 - $260,440
Income Estimation: 
$249,515 - $311,938
Income Estimation: 
$155,477 - $213,492
This job has expired.
Employees: Get a Salary Increase
View Core, Job Family, and Industry Job Skills and Competency Data for more than 15,000 Job Titles Skills Library

Job openings at WuXi AppTec

  • WuXi AppTec 2108 Couvet, NE
  • Overview WuXi AppTec is a trusted partner and contributor to the pharmaceutical and life sciences industries, providing R&D and manufacturing services that... more
  • 9 Days Ago

  • WuXi AppTec Middletown, DE
  • The Lead Facilities Maintenance Technician ensures the 24/7 operational readiness, reliability, and safety of mission-critical laboratory, data center, and... more
  • 9 Days Ago

  • WuXi AppTec Natick, MA
  • WuXi Biology is seeking a Bioinformatics Scientist (Senior or Principal level) with experience in Oligonucleotide Drug design. Oligonucleotide drug design ... more
  • 9 Days Ago

  • WuXi AppTec NE
  • Overview Le technicien de maintenance Utilities a pour mission de fournir un service de maintenance fiable et réactif aux installations techniques du site ... more
  • 11 Days Ago


Not the job you're looking for? Here are some other Senior Scientist II - Biophysics jobs in the Natick, MA area that may be a better fit.

  • Lila Sciences Cambridge, MA
  • Your Impact at LILA Lila Sciences is seeking a Computational Biophysics Scientist to help ensure that our AI agents can use biophysics tools in ways that a... more
  • 9 Days Ago

  • Spear Bio Woburn, MA
  • Spear Bio, founded in 2021, is a well-funded and rapidly growing biotech start-up headquartered in Woburn, Massachusetts. Our proprietary technology, Succe... more
  • 22 Days Ago

AI Assistant is available now!

Feel free to start your new journey!