Demo

Senior Scientist II - Biophysics

WuXi AppTec
Natick, MA Full Time
POSTED ON 11/21/2025 CLOSED ON 12/17/2025

What are the responsibilities and job description for the Senior Scientist II - Biophysics position at WuXi AppTec?

We are a fast-growing research and services division in WuXi AppTec and are working on developing cutting-edge multidisciplinary drug discovery platforms combining the latest technologies in biology, chemistry, biophysics, engineering, and informatics. We are seeking a highly motivated and collaborative biophysicist to play an integral role in expanding the capabilities at our site in Natick MA. This position is critical to the successful development, implementation and business operations of biophysics platforms and services for the business unit.

Responsibilities

  • Designs and executes novel SPR, TSA, and other biophysics studies, including protein-small molecule interactions, protein-protein interactions, and fragment screening.
  • Analyzes and interprets biophysical data.
  • Works closely with clients to establish assays.
  • Prepares scientific reports and presents scientific data.
  • Develops workflow and processes.
  • Mentors junior scientists in the lab.
  • Works broadly and flexibly with the biophysics business group across different geographic regions.
  • Contribute to troubleshooting, planning, and biophysics strategy as a key member of the biophysics group.
  • Develops and performs orthogonal target engagement, or additional binding assays in line with project requirements.

Qualifications

Experience / Education

  • Bachelor's with 14 years’ experience; Master's with 10 years’ experience, or PhD with 6 years’ experience. Master or PhD degree is preferred in Biochemistry or Biophysics.
  • Industry experience in Pharma/Biotech and/or drug R&D process is preferred.
  • Proven hands-on experience with developing and troubleshooting biophysical assays (SPR, MST, DSF/TSA, GCI, ITC and/or MS).
  • Deep understanding of binding kinetics and rigorous data analysis
  • Demonstrated understanding of complex scientific procedures and technical proficiency with in vitro assays.

Knowledge / Skills / Abilities:

  • Ability to demonstrate scientific creativity, critical thinking and fast learning capabilities.
  • Outstanding written and oral communication skills.
  • Interpersonal skills to seamlessly fit within a teamwork driven environment.
  • Ability to effectively communicate with internal team colleagues and external clients to promote world class service.
  • Must be able to read, write and understand English.

Physical Requirements:

  • Must be able to work in an office environment with minimal noise conditions.
  • Must be able to work in a lab setting with exposure to biohazards, chemicals
  • Must be able to wear appropriate PPE
  • Must be able to work in an environment with variable noise levels
  • Ability to stand/sit/walk for long periods
  • Ability to lift 10 lbs. routinely
  • Ability to crouch, bend, twist, and reach
  • Ability to push/pull 10 lbs. routinely
  • Clarity of Vision

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability

This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. Employees holding this position will be required to perform any other job-related duties as requested by Management.

Salary.com Estimation for Senior Scientist II - Biophysics in Natick, MA
$124,808 to $155,766
If your compensation planning software is too rigid to deploy winning incentive strategies, it’s time to find an adaptable solution. Compensation Planning
Enhance your organization's compensation strategy with salary data sets that HR and team managers can use to pay your staff right. Surveys & Data Sets

What is the career path for a Senior Scientist II - Biophysics?

Sign up to receive alerts about other jobs on the Senior Scientist II - Biophysics career path by checking the boxes next to the positions that interest you.
Income Estimation: 
$116,765 - $144,626
Income Estimation: 
$142,836 - $179,016
Income Estimation: 
$112,363 - $146,135
Income Estimation: 
$153,127 - $203,425
Income Estimation: 
$139,626 - $193,276
Income Estimation: 
$164,650 - $211,440
Income Estimation: 
$130,030 - $173,363
Income Estimation: 
$139,626 - $193,276
Income Estimation: 
$194,895 - $259,743
Income Estimation: 
$192,057 - $260,440
Income Estimation: 
$249,515 - $311,938
Income Estimation: 
$155,477 - $213,492
This job has expired.
Employees: Get a Salary Increase
View Core, Job Family, and Industry Job Skills and Competency Data for more than 15,000 Job Titles Skills Library

Job openings at WuXi AppTec

  • WuXi AppTec Middletown, DE
  • Seeking a motivated college student (Business or related field) for a summer internship within a pharmaceutical manufacturing operations team. This role pr... more
  • Just Posted

  • WuXi AppTec Middletown, DE
  • This summer internship offers hands-on experience in a fast-paced pharmaceutical manufacturing environment. You will assist with the provisioning, installa... more
  • 1 Day Ago

  • WuXi AppTec Middletown, DE
  • We are seeking a motivated and detail-oriented Document Control Intern to provide critical administrative and hands-on support during the peak construction... more
  • 1 Day Ago

  • WuXi AppTec San Diego, CA
  • We are looking for an accomplished in vivo immunology and autoimmune diseases expert to join our US team as a Director. This role serves as the scientific ... more
  • 2 Days Ago


Not the job you're looking for? Here are some other Senior Scientist II - Biophysics jobs in the Natick, MA area that may be a better fit.

  • The First Church of Christ, Scientist Boston, MA
  • Job Details Description Department: Office of the Chief Information Officer Summary Work as a member of the OCIO Service Team to resolve customer requests ... more
  • 18 Days Ago

  • The First Church of Christ, Scientist Boston, MA
  • Department: Christian Science Practitioner Activities SUMMARY The primary responsibility of the Senior Administration and Operations Coordinator is to supp... more
  • 18 Days Ago

AI Assistant is available now!

Feel free to start your new journey!