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Research Associate, Process Development

Wave Life Sciences
Lexington, MA Full Time
POSTED ON 11/7/2025
AVAILABLE BEFORE 12/6/2025
Job Description

Wave Life Sciences is a biotechnology company focused on unlocking the broad potential of RNA medicines to transform human health. Our RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation and deep insights in human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. Our toolkit of RNA-targeting modalities includes editing, splicing, RNA interference and antisense silencing, providing us with unmatched capabilities for designing and sustainably delivering candidates that optimally address disease biology. Our diversified pipeline includes clinical programs in Duchenne muscular dystrophy, Alpha-1 antitrypsin deficiency and Huntington’s disease, as well as a preclinical program in obesity. Driven by the calling to “Reimagine Possible”, we are leading the charge toward a world in which human potential is no longer hindered by the burden of disease.

Description

Wave Life Sciences is seeking a highly motivated Analytical Chemist to join its process development team in Lexington, Massachusetts. This is an ideal opportunity for an individual who is interested in cutting edge technologies and who thrives in a team-oriented, fast-paced, cross-disciplinary biotech environment. The candidate will take an active role in the analytical characterization of stereopure oligonucleotides for discovery and development-related activities.

Experience

  • Requires a BS/MS in chemistry, biochemistry, or related discipline with 1-5 years of laboratory experience.
  • Prior experience in oligonucleotide analysis is preferred but not required.

Responsibilities

  • Perform analytical QC of oligonucleotides by UV, endotoxin, osmolality, pH, UPLC, and LC-MS
  • Operate, maintain, and troubleshoot instrumentation such as UPLC, LC-MS, and additional benchtop equipment
  • Summarize/ present analytical findings at team meetings
  • Maintain detailed written and electronic records of experimental protocols and data in accordance with company policy
  • Maintain oligonucleotide inventory
  • Establish and maintain excellent working relationships within the team
  • Follow SOPs and adapt to new techniques and protocols

Key Skills

  • Understanding of analytical techniques such as UPLC and LC-MS
  • Demonstrable organizational and time management skills with the ability to multitask
  • Ability to be productive in a dynamic, fast-paced environment
  • Ability to work independently and within a team

Pay Range External Disclosure Statement

The annual base salary for this position is $68,000 - $97,000.

The range provided is based on what we believe is a reasonable estimate for the annual base salary pay range for this position at the time of posting. Actual annual base salary will vary based on several factors including, but not limited to, relevant skills, experience, qualifications, position criticality, and internal equity. This position is eligible for a discretionary annual bonus and discretionary stock-based long-term incentives. In addition to compensation, Wave offers a comprehensive and competitive range of benefits designed to support our employees’ and their families physical and financial health and overall well-being. These include, but are not limited to, company-sponsored medical, dental, vision, life, long and short-term disability insurances, generous paid time off (including a week-long company shutdown in the Summer and the Winter), 401K participation with matching contributions, and Employee Stock Purchase Program.

Wave Life Sciences provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, disability or genetics. In addition to federal law requirements, Wave Life Sciences complies with applicable state and local laws governing nondiscrimination in employment in every location in which the company has facilities. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Wave Life Sciences expressly prohibits any form of workplace harassment based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status. Improper interference with the ability of Wave Life Sciences’ employees to perform their job duties may result in discipline up to and including discharge.

We value our relationships with professional recruitment firms. To protect the interests of all parties, and given the large volume of inquiries received from third-party placement agencies, we are not able to respond to all agency inquiries. We do not accept unsolicited resumes from any source other than directly from candidates for current or future positions. Submission of unsolicited resumes in advance of a signed agreement between our company and a placement agency does not create an implied obligation and, if an unsolicited candidate represented by a placement agency is hired, we are not obligated to pay a fee. Only approved recruitment firms will be allowed to provide services to Wave Life Sciences, USA.

Salary : $68,000 - $97,000

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