What are the responsibilities and job description for the Associate - Sr. Director, Oligonucleotide Chemistry, Woburn position at Vivatides Therapeutics Inc.?
Position Summary:
As an exciting start-up, we offer amazing opportunity to develop the next generation RNA therapeutics. We are seeking a well-organized and self-motivated senior scientist to join our company site in Woburn, MA. The successful candidate will be a key member of the drug discovery group and will lead efforts to advance siRNA/ASO therapeutics to treat intractable diseases. Strong knowledge of oligonucleotide drug design and experience in organic chemistry of oligonucleotide precursors, respective delivery vehicles and methods is a must. Experience in oligonucleotide post-conjugation methods is a strong plus. Experience of work with oligo synthesizers is a plus but not required. Proven track record of leadership of successful projects in oligonucleotide drug discovery and strong publication record of scientific papers and patents.
Primary Responsibilities:
- Chemistry platform design and refining.
- CMC planning.
- Direct chemistry informatics (internal databases, literature and patent search).
- Drafting of patent applications.
- Oversee team performance.
- Manage FFS/FTE projects with CROs.
- Follow and further refine company standards of data collection, presentation, and QC.
- May need to establish new specialized chemistry units, screen/recruit candidate chemists.
Qualifications:
- Ph.D. in Organic or Medicinal Chemistry.
- Minimum of 5 years of experience in oligonucleotide drug discovery, with at least 2 years in a leadership role.
- Deep understanding of oligonucleotide and precursor synthesis, modification, purification, and conjugation mechanisms.
- Familiarity with analytical methods and quality standards in oligonucleotide drug development.
- Strong project management skills and cross-functional communication abilities.
E-mail: HRTA@vivatides.com