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Sr. Director, AI Strategy & Enterprise Enablement

Viridian Therapeutics, Inc.
Waltham, MA Full Time
POSTED ON 12/1/2025 CLOSED ON 12/31/2025

What are the responsibilities and job description for the Sr. Director, AI Strategy & Enterprise Enablement position at Viridian Therapeutics, Inc.?

At Viridian, we are focused on developing best-in-class medicines for people living with autoimmune and rare diseases. Leveraging our team’s expertise in antibody discovery and engineering, we have created a robust pipeline of differentiated investigational therapeutic candidates for well-validated targets.


Reporting to the VP, IT & Facilities the Sr. Director, AI Strategy & Enterprise Enablement will be responsible for shaping Viridian’s vision and roadmap for how AI can transform the way we operate, make decisions, and serve patients. This role will partner across Research, Development, Medical Affairs, Commercial, HR, and Corporate functions to identify opportunities where intelligent systems can drive measurable impact. This role will act as a bridge between technology and business strategy, helping Viridian responsibly adopt emerging technologies that enhance productivity, speed, and innovation across the organization


This role is based in our Waltham, MA headquarters. Our office-based employees are required to work in the office three (3) days a week.


Responsibilities (including, but not limited to):

Strategic Leadership & Vision

  • Define and lead Viridian’s AI and intelligent automation strategy aligned with enterprise priorities and long-term growth plans
  • Serve as a trusted advisor to functional leaders on how AI and data-driven insights can optimize decision-making and operational excellence
  • Establish an AI governance framework to ensure responsible, ethical, and compliant use of technology

AI Risk Management & Security

  • Develop and implement a comprehensive AI risk management framework to identify, assess, and mitigate risks associated with AI systems, including model bias, data privacy, and cybersecurity threats
  • Collaborate with IT, Legal, and Compliance teams to ensure AI solutions adhere to internal policies and external regulations (e.g., HIPAA, GDPR)
  • Monitor and evaluate the ethical implications of AI deployments, ensuring transparency, accountability, and fairness in all intelligent systems
  • Establish protocols for incident response and remediation in the event of AI-related failures or breaches
  • Regularly review and update risk management practices to address emerging threats and evolving regulatory requirements


Enterprise Enablement & Partnerships

  • Partner with leaders across R&D, Clinical, Medical, and Commercial functions to identify and prioritize AI use cases that deliver high-value outcomes
  • Collaborate with HR, Finance, and Corporate Communications to improve workforce efficiency, candidate experience, and employee engagement through intelligent systems
  • Build strategic partnerships with AI vendors, academic institutions, and industry consortiums to bring external innovation into Viridian

Execution & Change Management

  • Oversee implementation of enterprise-level AI initiatives and digital transformation projects from concept to adoption
  • Work closely with IT and Data Engineering to ensure robust data foundations that enable advanced analytics and automation
  • Lead change management initiatives to build organizational understanding, trust, and literacy around AI

Measurement & Impact

  • Define success metrics and key performance indicators (KPIs) for AI adoption and enterprise enablement
  • Quantify the business impact of AI initiatives, efficiency gains, decision speed, data quality, or cost savings
  • Regularly brief the Executive Leadership Team on progress, learnings, and emerging opportunities


Qualifications:

  • Bachelor’s degree required; advanced degree (MBA, MS, PhD) preferred in a relevant field such as Business, Data Strategy, or Life Sciences
  • 15 years of progressive experience in technology strategy, enterprise analytics, or AI enablement within biotechnology, life sciences, or a related sector
  • Proven ability to translate emerging technologies into business outcomes
  • Demonstrated experience building cross-functional alignment and leading through influence in matrixed organizations
  • Understanding of AI and data governance, data ethics, and compliance frameworks (HIPAA, GDPR)
  • Demonstrated familiarity with cloud platforms (such as AWS, Azure, or Google Cloud Platform), data science tools, machine learning frameworks, and enterprise data architecture to effectively guide the evaluation, selection, and implementation of advanced AI solutions
  • Excellent communication and storytelling skills with the ability to simplify complex topics for executive audiences
  • Efficient independent worker with ability to focus and drive for results
  • Demonstrates strong attention to detail while effectively managing multiple tasks in a fast-paced environment
  • Strong commitment to ethical standards
  • Proficient with Microsoft Office suite (i.e., Word, PowerPoint, Excel, Outlook, SharePoint, etc.)
  • Ability to travel up to 10%
  • The salary range for this position is commensurate with experience




Viridian offers a comprehensive benefits package including:

  • Competitive pay and stock options for all employees
  • Competitive medical, dental, and vision plans
  • Fertility and mental health programs
  • Short- and long-term disability coverage
  • Life, Travel and AD&D
  • 401(k) Company Match with immediate company vest
  • Employee Stock Purchase plan
  • Generous vacation plan and paid company holiday shutdowns
  • Various mental, financial, and proactive physical health programs covered by Viridian

Viridian Therapeutics, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination, harassment, or retaliation of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by Federal, State, and Local laws. Viridian will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.


Viridian Therapeutics, Inc participates in E-Verify, the federal program for electronic verification of employment eligibility.

Salary : $229,000 - $280,000

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Job openings at Viridian Therapeutics, Inc.

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