What are the responsibilities and job description for the Scientist - Macrocycle Design position at Vilya?
Vilya is a computational biotechnology company creating a novel class of medicines to precisely target disease biology. We believe computational approaches are an integral, if not foundational, component of drug discovery and development.
We are harnessing the power of our platform to go after previously impossible targets in an array of indications. Vilya’s ultimate goal is to solve some of the most challenging unmet medical needs that exist today.
Our Vision: Harness a revolution in technology and biology to better human health.
Our Mission: Build an independent, leading biotech company founded on intelligent drug design to cure the incurable.
We are seeking a Scientist, Macrocycle Design to apply state-of-the-art de novo design methodologies to computationally discover, develop, and evaluate therapeutic macrocycles. As a member of the design team in Seattle WA, you will leverage your knowledge of cutting edge methods in molecular design to augment Vilya’s existing design platform.
Vilya is a team-first organization, and we believe onsite work is essential to how we collaborate, move quickly, and build a strong culture. This is an onsite position in our Seattle office. Join us and help make a difference for patients!
Responsibilities
We are harnessing the power of our platform to go after previously impossible targets in an array of indications. Vilya’s ultimate goal is to solve some of the most challenging unmet medical needs that exist today.
Our Vision: Harness a revolution in technology and biology to better human health.
Our Mission: Build an independent, leading biotech company founded on intelligent drug design to cure the incurable.
We are seeking a Scientist, Macrocycle Design to apply state-of-the-art de novo design methodologies to computationally discover, develop, and evaluate therapeutic macrocycles. As a member of the design team in Seattle WA, you will leverage your knowledge of cutting edge methods in molecular design to augment Vilya’s existing design platform.
Vilya is a team-first organization, and we believe onsite work is essential to how we collaborate, move quickly, and build a strong culture. This is an onsite position in our Seattle office. Join us and help make a difference for patients!
Responsibilities
- Collaborate with multi-disciplinary teams in the discovery and development of macrocyclic molecules with potency, selectivity, and in vivo stability using structure-guided approaches.
- Apply de novo design methods and integrated computational pipelines that generate macrocycle designs in support of discovery and hit optimization programs.
- Analyze data from experimental and computational assays to improve methodology throughout Vilya’s therapeutic discovery platform.
- Innovate Vilya’s computational design platform by building state-of-art de novo design workflows
- Ph.D. in a scientific or engineering discipline at the intersection of computational molecular design, medicinal chemistry, and drug discovery
- Hands-on experience with state-of-the-art protein design tools applied to de novo design of therapeutic molecules in conjunction with a deep understanding of molecular structure analysis methods
- Extensive hands-on experience with parallel job execution and high performance computing systems
- Expertise in working with high-level programing languages such as Python
- Expertise in integrating computational models into scalable and reproducible workflows
- Adept at working in a multi-disciplinary team
- Opportunity to work in a disruptive startup with a talented, experienced, and dedicated team
- 401(k) plan with employer matching for contributions
- Stock options
- Excellent medical, dental, and vision coverage
- Open, flexible vacation policy
- Support to attend professional conferences meaningful to your career growth
- Monthly cell phone and internet stipend
- Monthly wellness and commuter stipend
Salary : $120,000 - $160,000