What are the responsibilities and job description for the HPLC Analyst / Analytical Chemist position at Vanguard Laboratory?
HPLC Analyst / Analytical Chemist – Peptide Testing
Vanguard Laboratory | Olympia, Washington
Full-time and part-time schedules available
Vanguard Laboratory is hiring an analyst to prepare peptide samples, operate HPLC systems, and review chromatographic data in a busy analytical laboratory.
We are looking for someone who enjoys hands-on bench work, stays organized through large sample batches, and can produce accurate results efficiently. Your main responsibilities will be sample preparation, HPLC analysis, peak integration, calculations, and documenting results.
Hands-on HPLC experience is required. Previous peptide testing experience is preferred, but we can train an experienced HPLC analyst on our peptide methods.
What You’ll Do
- Prepare peptide samples for identity, chromatographic purity, and quantity testing.
- Accurately weigh materials, reconstitute samples, prepare dilutions, and track preparation factors.
- Prepare reference standards, calibration solutions, controls, mobile phases, and reagents.
- Build and run HPLC sequences containing samples, standards, blanks, and quality controls.
- Process large batches of chromatographic data, review peak integration, evaluate calibration curves, and calculate results.
- Check retention times, peak shape, resolution, baseline quality, carryover, and replicate agreement.
- Recognize questionable results, preparation errors, failed controls, and instrument problems.
- Perform routine HPLC maintenance and troubleshoot leaks, pressure changes, poor chromatography, and retention-time shifts.
- Maintain complete preparation records and data packages for technical review and reporting.
- Coordinate with other analysts to meet turnaround times and keep instruments productive.
This is a production-testing position. You should be comfortable performing repetitive preparation work accurately, managing multiple batches, and following samples through preparation, analysis, and data processing.
Required Experience
- Practical HPLC or UHPLC experience in a commercial, pharmaceutical, supplement, food, environmental, research, or other working laboratory.
- Experience preparing samples, standards, and serial dilutions.
- Experience reviewing chromatograms, integrating peaks, and using calibration curves for quantitative analysis.
- Strong organization, accurate calculations, and clear documentation.
- Ability to work efficiently while following methods and quality-control requirements.
- A degree in chemistry, biochemistry, or a related field, or equivalent relevant laboratory experience.
Helpful Experience
- Peptide, pharmaceutical, small-molecule, or nutritional supplement testing.
- Agilent HPLC systems and ChemStation or OpenLab software.
- Processing large sample batches and meeting commercial turnaround times.
- HPLC troubleshooting and routine maintenance.
- ISO/IEC 17025, GMP, or GLP laboratory experience.
- LC-MS or LC-MS/MS experience.
You do not need experience with every instrument in our laboratory to qualify.
Available Schedules
Tell us which schedule or schedules you can work:
- Saturday–Tuesday: four 10-hour shifts.
- Thursday–Sunday: four 10-hour shifts.
- Monday–Friday: 2:30 p.m.–11:00 p.m.
- Friday–Sunday: three 12-hour shifts.
- Saturday–Sunday: part-time.
These are ongoing shift assignments. Please apply for a schedule you can maintain long term.
Compensation and Benefits
$22–$28 per hour, depending on relevant HPLC experience, sample-preparation skills, data-analysis experience, and ability to work independently.
Benefits for eligible employees include:
- Employer-matched 401(k).
- Health, dental, vision, and life-insurance options.
- Paid vacation and parental leave.
- Professional-development assistance and technical training.
- Merit-based raises.
Employees may also earn $500–$2,000 for successfully implementing a new method, depending on complexity, contribution, validation, documentation, and laboratory approval.
About Vanguard Laboratory
Vanguard Laboratory is an established, family-owned, ISO/IEC 17025:2017 accredited analytical laboratory in Olympia, Washington. We test peptides, pharmaceuticals, supplements, food, drinking water, environmental samples, and other products.
How to Apply
Submit your resume and include a short note answering:
- Which available schedules can you work?
- Which HPLC instruments and software have you personally used?
- What samples have you prepared, and have you independently processed chromatographic data?
Pay: $22.00 - $30.00 per hour
Benefits:
- 401(k)
- 401(k) matching
- Dental insurance
- Health insurance
- Life insurance
- Paid time off
- Parental leave
- Professional development assistance
- Retirement plan
- Vision insurance
Application Question(s):
- Did you submit a cover letter? Required for Application.
Experience:
- HPLC: 1 year (Preferred)
Location:
- Olympia, WA 98502 (Preferred)
Ability to Commute:
- Olympia, WA 98502 (Required)
Work Location: In person
Salary : $22 - $30