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Data Scientist II, O'Donnell Brain Institute

UT Southwestern Medical Center
Dallas, TX Full Time
POSTED ON 4/10/2026 CLOSED ON 4/12/2026

What are the responsibilities and job description for the Data Scientist II, O'Donnell Brain Institute position at UT Southwestern Medical Center?

WHY UT SOUTHWESTERN?
With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas-Fort Worth according to U.S. News & World Report, we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you'll discover a culture of teamwork, professionalism, and a rewarding career! 

JOB SUMMARY
Works under general direction to provide analysis and develops algorithms and software for clinical and/or basic research problems. Impacts data acquisition, management, and analysis in basic, translational, and clinical research, including clinical trials. 

The newly established Program for Memory Longevity (PML), led by Attila Losonczy in the Peter O’Donnell Jr. Brain Institute at the University of Texas Southwestern Medical Center (UTSW) in Dallas, in collaboration with the Paninski and Peterka labs in the Zuckerman Institute (ZI), Columbia University, New York and the International Brain Lab (IBL) is seeking a full-time Research Software Engineer. The Research Software Engineer will work closely with these labs to help develop and maintain software tools, in particular for the analysis and interpretation of large-scale imaging data. The ideal candidate will play an important role in translating research code into robust and easy-to-use software packages, as well as contribute to the understanding and use of imaging data. The primary location is at UTSW, including collaborative visits at ZI, New York.

Main responsibilities include:

  • Develop and maintain software packages for the analysis of functional optical imaging data (e.g., one- and two-photon calcium and voltage imaging).
  • Develop and maintain local and browser-based user interfaces for these packages.
  • Work closely with other research software engineers to coordinate APIs and wrappers to link the optical imaging analysis suites to other 

    synchronously monitored signals (e.g. electrophysiology or behavioral videography)

     

  • Support the adoption and use of the software by the worldwide scientific community through dissemination efforts, including publishing written documentation and video tutorials, and assisting with workshops
  • Work closely with machine learning researchers at UTSW and ZI to incorporate new algorithms into the software packages

BENEFITS
UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:

  • PPO medical plan, available day one at no cost for full-time employee-only coverage
  • 100% coverage for preventive healthcare-no copay
  • Paid Time Off, available day one
  • Retirement Programs through the Teacher Retirement System of Texas (TRS)
  • Paid Parental Leave Benefit
  • Wellness programs
  • Tuition Reimbursement
  • Public Service Loan Forgiveness (PSLF) Qualified Employer
  • Learn more about these and other UTSW employee benefits!

EXPERIENCE AND EDUCATION

Required

  • Education
    Master's Degree M.S. in Computer Science, Bioinformatics, (Bio)mathematics, (Bio)statistics, Physics, Electrical Engineering, or related field or 
    Bachelor's Degree B.S. with demonstrated experience in broadly defined areas of bioinformatics. 
     
  • Experience
    2 years of post-graduation experience in data analysis and/or scientific software development for a Master‿s degree 
    4 years of post-graduation experience in data analysis and/or scientific software development for a Bachelor‿s degree 
     

JOB DUTIES

  • Analyzes and develops formalisms, algorithms and software for applications in biomedical research.
  • Develops and maintains software tools and infrastructure for resolving specific problems.
  • Performs the development, testing and revision of programs in a team with diverse bioinformatics expertise.
  • Advises and assists users and other personnel in analyzing, defining and resolving computational problems.
  • Performs other duties as assigned.

SECURITY AND EEO STATEMENT

Security
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.

EEO
UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
 

Salary : $1,000 - $1,000,000

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