Demo

Sr. Mechanical Engineer, Design

Until
San Francisco, CA Full Time
POSTED ON 10/17/2025 CLOSED ON 12/16/2025

What are the responsibilities and job description for the Sr. Mechanical Engineer, Design position at Until?

Until is a moonshot company building a “pause button” for biology. Our near-term focus is organ-scale reversible cryopreservation: preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant. By solving this grand challenge, we’re laying the foundation for whole-body reversible cryopreservation, giving patients a bridge to future cures.

To achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.

We envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive.

About The Role
The hardware we need to accomplish our mission does not exist, so we must make it ourselves. As a mechanical engineer spearheading our mechanical design efforts, you'll be tasked with designing everything from heat exchangers to clinical grade perfusion devices.

About You

  • Track record of exceptional engineering abilities, with an emphasis on shipping completed systems from sketch to final part with minimal outside direction
  • 6 years experience/graduate level in Mechanical Engineering or equivalent
  • Highly proficient in DFM, CAD, FEA (Fusion 360 Preferred)
  • Highly proficient with common rapid prototyping and manufacturing processes (especially multiple additive methods, CNC machining and laser cutting)
  • Ability to spec a system based on first principles, design it, perform component selection, prototype, and optimize for manufacturing
  • Desire to join a fast-paced, scrappy engineering team




Preferred Qualifications

  • Experience leading highly technical, multidisciplinary teams
  • Class III Medical Device experience
  • Industrial Design & Engineering Experience




While this represents our expected range based on market data, final compensation will be determined based on your specific qualifications and may be outside this range. Please keep in mind that the equity portion of the offer is not included in this estimate.

Salary : $145,000 - $210,000

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