Process Chemist

Adesis Inc. - a subsidiary of Universal Display Corporation (Nasdaq: OLED), a global leader in organic light emitting diodes - is a premier contract development and manufacturing organization (CDMO) accelerating our clients’ success in the biotech, pharmaceutical and specialty chemistry industries through our innovative chemistry and solutions.

Adesis Inc. encompasses almost 100,000 square feet of state-of-the-art laboratory and manufacturing space in two U.S. locations - New Castle and Wilmington, DE, centrally located in the Mid-Atlantic biotech/ pharmaceutical hub.

Our business model provides clients with organic chemistry services in three areas: early-stage research, scale-up and development, and specialty manufacturing. We specialize in organic and organometallic synthesis, from milligrams to multi-kilogram quantities, and our exceptional technical team prides ourselves in our ability to solve challenging chemistry problems for our growing client base.

Adesis is an extraordinary company looking for extraordinary talent! Our mission is to accelerate our clients’ success through innovative chemistry and solutions, and we offer promising careers in an inclusive work environment aligned with our values of innovation, ownership and integrity.

Job Summary:
The manufacturing Process Chemist works both independently and as part of a team to assist in the development, optimization, and technology transfer of commercial manufacturing compounds. The position involves set-up, use, and cleaning of various laboratory equipment as well as running established protocols with the guidance of chemists and senior technical staff.

Key Responsibilities:

• Develop robust processes for the target compounds to ensure safe and reproducible processes.

• Develop alternate synthetic routes to target molecules and modify reactants and/or equipment as required.

• Solve complex chemical problems which may arise during process development, optimization or scale up of processes.

• Understand the concepts of reaction kinetics, design of experiments, solubility and crystallization, mass transfer, heat transfer and process safety to ensure critical process parameters are identified.

• Accountable for documentation to ensure the consistent manufacture of products; including batch records, production instructions, and development / qualification reports.

• Performs other related duties as assigned by Management.

Technical and Specialized Equipment:

• NMR

• (UP)LC/MS

• EasyMax, PolyBLOCK

• Jacketed reactors

• GC/MS

• Automated Chromatography Systems

• Hydrogenation equipment

Required Qualifications:

• BS or MS in Chemistry or related field required.

• At least 2 - 5 years’ experience in technical production, R&D, and/or new product development experience required.

• Ability to define problems, collect data, establish facts, and draw valid conclusions. Interpretation of technical instructions from disparate information sources, and deal with several abstract and concrete variables.

• Ability to work within a fast-paced, dynamic and team environment.

• Working knowledge of ISO-9001, cGMP, and/or ICH Q7 in pharma or chemical regulated environments preferred.

• Knowledge of Process Improvement methodology (ie., Lean Manufacturing, Six Sigma, and/or TOC) a plus.

• Experience with or ability to master the use of modern research tools such as EasyMax, PolyBlock, Continuous Flow Reactors, and in-situ process monitoring a plus.

• Strong computer skills in standard & scientific systems, such as Microsoft Word, Excel, PowerPoint, ChemDraw, Reaxys and Scifinder.

• Experience with Polymer chemistry a plus.