What are the responsibilities and job description for the Research Associate II, Cell Production & Process Development (iPSC) position at United Therapeutics Corporation?
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The job details are as follows:
Who We Are
We are the first publicly-traded biotech or pharmaceutical company to take the form of a public benefit corporation. Our public benefit purpose is to provide a brighter future for patients through the development of novel pharmaceutical therapies; and technologies that expand the availability of transplantable organs.
United Therapeutics (Nasdaq: UTHR) seeks to travel down the corridors of indifference to develop treatments for rare, deadly diseases. We were founded in 1996 by a family seeking a cure for their daughter’s pulmonary arterial hypertension (PAH). Today, we have six FDA-approved therapies that treat PAH, pulmonary hypertension associated with interstitial lung disease (PH-ILD) and neuroblastoma, a rare pediatric cancer. Our near-term pipeline seeks to develop additional therapies for PAH and pulmonary fibrosis (PF).
The cure for end-stage life-threatening diseases like PAH, PH-ILD, PF, and many others is an organ transplant, but only a small percentage of donated organs are available to address the vast need. For this reason, we are working to create manufactured organs to address the shortage of kidneys, hearts, lungs, and livers available for transplant. We believe an unlimited supply of tolerable, transplantable organs will eliminate the transplant waiting list and cure end-stage organ diseases for which transplant is not currently an option.
Millions worldwide are living with chronic kidney disease or diabetes. Management and maintenance therapies are ongoing, expensive, and often undermine the person’s quality of life. Their only hope for a cure is an kidney transplant. Unfortunately, the shortage of available kidneys causes patients to spend an average of 5 or more years on the waitlist, and many die before receiving surgery. At IVIVA, we are working to transform the status quo by developing fully implantable bioartificial kidneys. Our goal is to develop a cure that can allows patients with kidney dysfunction to lead a normal life
Who You Are
There has never been a more exciting time to join IVIVA, a United Therapeutics company. This position offers someone the opportunity of a lifetime – to see a product into something real, an opportunity to create a human kidney equivalent and save lives on a scale before unknown. The Research Associate II – Cell production and Process Development will perform and contribute to the design of cell studies as well as execute analytical methods to support the production and process development of iPS-derived cells and cellularized 3D scaffolds for the development of autologous 3D printed tissue engineered organs.
This role is located 100% onsite in Medford, Massachusetts.
The salary for this position ranges from $68,500 to $95,000 per year. and reflects our good-faith estimate of the compensation for this role at the time of posting. An employee’s position within the salary range will be based on factors such as education, qualifications, experience, skills, geographic location, and business needs, as well as other factors permitted by law at the time of posting. This range may be modified in the future based on company and market factors.
Eligible employees may participate in the Company’s comprehensive benefits suite of programs, including medical / dental / vision / prescription coverage, employee wellness resources, savings plans (401k and ESPP), paid time off & paid parental leave benefits, disability benefits, and more. For additional information on Company benefits, please visit https://www.unither.com/careers/benefits-and-amenities
United Therapeutics Corporation is an Equal Opportunity Employer, including veterans and individuals with disabilities.
The job details are as follows:
Who We Are
We are the first publicly-traded biotech or pharmaceutical company to take the form of a public benefit corporation. Our public benefit purpose is to provide a brighter future for patients through the development of novel pharmaceutical therapies; and technologies that expand the availability of transplantable organs.
United Therapeutics (Nasdaq: UTHR) seeks to travel down the corridors of indifference to develop treatments for rare, deadly diseases. We were founded in 1996 by a family seeking a cure for their daughter’s pulmonary arterial hypertension (PAH). Today, we have six FDA-approved therapies that treat PAH, pulmonary hypertension associated with interstitial lung disease (PH-ILD) and neuroblastoma, a rare pediatric cancer. Our near-term pipeline seeks to develop additional therapies for PAH and pulmonary fibrosis (PF).
The cure for end-stage life-threatening diseases like PAH, PH-ILD, PF, and many others is an organ transplant, but only a small percentage of donated organs are available to address the vast need. For this reason, we are working to create manufactured organs to address the shortage of kidneys, hearts, lungs, and livers available for transplant. We believe an unlimited supply of tolerable, transplantable organs will eliminate the transplant waiting list and cure end-stage organ diseases for which transplant is not currently an option.
Millions worldwide are living with chronic kidney disease or diabetes. Management and maintenance therapies are ongoing, expensive, and often undermine the person’s quality of life. Their only hope for a cure is an kidney transplant. Unfortunately, the shortage of available kidneys causes patients to spend an average of 5 or more years on the waitlist, and many die before receiving surgery. At IVIVA, we are working to transform the status quo by developing fully implantable bioartificial kidneys. Our goal is to develop a cure that can allows patients with kidney dysfunction to lead a normal life
Who You Are
There has never been a more exciting time to join IVIVA, a United Therapeutics company. This position offers someone the opportunity of a lifetime – to see a product into something real, an opportunity to create a human kidney equivalent and save lives on a scale before unknown. The Research Associate II – Cell production and Process Development will perform and contribute to the design of cell studies as well as execute analytical methods to support the production and process development of iPS-derived cells and cellularized 3D scaffolds for the development of autologous 3D printed tissue engineered organs.
- Perform and assist ongoing optimization of the processes to expand and differentiate iPS cells into various cell types under limited oversight
- Collaborate with scientists to perform and optimize cellular processes to support the production of iPS-derived renal cells
- Assist in cell studies to address technical and scientific challenges to expansion and differentiation of iPSC-derived cells
- Prepare, record and manage materials, reagents, and solutions to support cell production and tissue engineering experiments
- Write and update standard operating procedures and batch records for various differentiation, isolation, expansion and QC processes
- Record all laboratory data in the in-house data management system(s)
- Write and update standard operating procedures for operation and maintenance of laboratory equipment
- Conduct the technical transfer of assays into the production team or to internal manufacturing, as needed
- Maintain smooth operations of the lab, including maintenance of lab supplies, monitoring of equipment, providing general lab support and helping identify areas for improvement
- Follow proper procedures regarding laboratory safety, use of personal protective equipment, and handling of biohazard materials, including human or animal cells and tissues
- Meet 1:1 with managers to review results and progress
- 2 years of experience in a cell biology, developmental biology or biomedical engineering environment with a Bachelor’s degree in cellular biology, developmental biology, biomedical engineering or related field
- Aseptic Technique and mammalian cell culture
- Knowledge of cell biology
- Ability to initiate and manage day-to-day tasks effectively, including multi-tasking, flexibility and adaptability
- Ability to independently follow experimental methods and protocols
- Technical expertise in iPS culture methods
- Comfortable working in a hands-on laboratory environment and have good attention to detail and good lab practice
- 0 years of experience in a cell biology, developmental biology or biomedical engineering environment with a Master’s degree in cellular biology, developmental biology, biomedical engineering or related field
- Knowledge of flow cytometry
- Technical experience in cell bioreactor culture
- Technical expertise in iPS-differentiation methods
This role is located 100% onsite in Medford, Massachusetts.
The salary for this position ranges from $68,500 to $95,000 per year. and reflects our good-faith estimate of the compensation for this role at the time of posting. An employee’s position within the salary range will be based on factors such as education, qualifications, experience, skills, geographic location, and business needs, as well as other factors permitted by law at the time of posting. This range may be modified in the future based on company and market factors.
Eligible employees may participate in the Company’s comprehensive benefits suite of programs, including medical / dental / vision / prescription coverage, employee wellness resources, savings plans (401k and ESPP), paid time off & paid parental leave benefits, disability benefits, and more. For additional information on Company benefits, please visit https://www.unither.com/careers/benefits-and-amenities
United Therapeutics Corporation is an Equal Opportunity Employer, including veterans and individuals with disabilities.
Salary : $68,500 - $95,000