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Post Doc (6)

UMass Chan Medical School
Worcester, MA Full Time
POSTED ON 10/30/2026
AVAILABLE BEFORE 11/27/2026
Postdoctoral position in Gut-Brain Communication

Alkema Laboratory | Department of Neurobiology | UMass Chan Medical School

We're looking for a motivated, creative postdoctoral fellow to join the Alkema laboratory in the Department of Neurobiology at UMass Chan Medical School. If you're excited by questions about how nervous systems generate complex behaviors and adapt them to changes in the internal and external environment, we'd love to hear from you.

Our research uses Caenorhabditis elegans to address two complementary questions. First, we investigate how neuromodulators and co-transmitters generate behavioral states and control transitions between them. Second, we examine how the gut microbiota and microbial metabolites influence neural function, physiology, and behavior.

These projects explore the mechanisms by which internal state, environmental conditions, and microbial signals are integrated by the nervous

system. We combine genetics, molecular biology, quantitative behavioral analysis, neural imaging, optogenetics, bacterial genetics, and metabolomics.

The successful candidate will have considerable freedom to develop an independent research direction

within either of these areas or at their intersection. Our lab is a collaborative and intellectually engaging place to work, where curiosity, creativity, and experimental rigor are all valued — and where you'll have colleagues invested in your growth as a scientist. You'll also be part of a, interactive research

community in the Department of Neurobiology at UMass Chan, with access to advanced imaging, genomic, metabolomic, and computational resources.

We're Looking For Someone With

  • A Ph.D. in neurobiology, microbiology, molecular biology, genetics, metabolism, bioinformatics, or a related field
  • Previous peer-reviewed publications
  • Strong experimental, analytical, and scientific-writing skills
  • The ability to work both independently and collaboratively
  • An interest in neuromodulation, behavior, or microbiome-host communication
  • Previous experience with C. elegans is helpful but not required.

Applicants with backgrounds in neuroscience, microbiology,

microbial genetics, imaging, metabolomics, or quantitative biology are encouraged to apply.

Postdoctoral fellows will be actively involved in manuscript and grant writing. Training and mentorship in grant writing will be provided, and fellows will be encouraged to develop and submit their own fellowship and research proposals.

To Apply, Please Send

  • A cover letter describing your research background, interests, and reasons for applying
  • A curriculum vitae, including a complete publication list
  • Contact information for three references

About

If you're interested or just want to learn more, please feel free to reach out with a CV and a short note about your background and interests to:

Dr. Mark Alkema

Department of Neurobiology

UMass Chan Medical School

Worcester, Massachusetts

mark.alkema@umassmed.ed

The University of Massachusetts Chan Medical School welcomes all qualified applicants and complies with all state and federal anti-discrimination laws.

Salary : $72,960

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