Postdoctoral Appointee – Large scale RNA production for Structural Biology of RNA

We invite applications for a postdoctoral position in working at Advanced Protein Characterization Facility (APCF) in the X-ray Science Division at Argonne National Laboratory. The selected candidate will participate in RNA project for structural characterization of RNA by SAXS, x-ray crystallography, and Cryo-EM. The main role for the project is to produce RNA samples in large scale by using in vitro transcription with T7 RNA polymerase, subsequent purification necessary for SAXS, MX and Cryo-EM. The work requires experience in molecular biology for basic cloning and protein expression (utilizing E. coli), nucleic acid and protein purification. Preparation of proteins needed during RNA production, such nucleases, phosphatase, RNase inhibitors as well as RNA chaperones used for crystallization are also part of duty. Involvement in the research pertinent to specific RNA targets will be expected as well, along with presentation of findings to the community through publications and presentations. Position Requirements Ph.D. completed in the past 5 years or soon to be completed in Molecular Biology, Biochemistry, Structural Biology, Biotechnology, Protein Engineering, Microbiology, or a related field Strong molecular biology skills (cloning, vector design, transformation), protein and nucleic acid prep-scale purification and analysis, and quantitative data analysis Excellent communication and teamwork capabilities, with a track record (or potential) in writing publications and presenting scientific results Ability to model Argonne’s core values of impact, safety, respect, integrity, and teamwork Interpersonal skills, oral and written communication skills, and ability to interact with people at all levels both within and outside the laboratory Preferred Knowledge, Skills, and Experience Knowledge of in RNA biology Experience with RNA CryoEM/crystallography/SAXS Prior experience with high-throughput or computational protein design/screening techniques Job Family Postdoctoral Job Profile Postdoctoral Appointee Worker Type Long-Term (Fixed Term) Time Type Full time The expected hiring range for this position is $72,879.00-$121,465.00. Please note that the pay range information is a general guideline only. The pay offered to a selected candidate will be determined based on factors such as, but not limited to, the scope and responsibilities of the position, the qualifications of the selected candidate, business considerations, internal equity, and external market pay for comparable jobs. Additionally, comprehensive benefits are part of the total rewards package. Click here to view Argonne employee benefits! As an equal employment opportunity employer, and in accordance with our core values of impact, safety, respect, integrity and teamwork, Argonne National Laboratory is committed to a safe and welcoming workplace that fosters collaborative scientific discovery and innovation. Argonne encourages everyone to apply for employment. Argonne is committed to nondiscrimination and considers all qualified applicants for employment without regard to any characteristic protected by law. Argonne employees, and certain guest researchers and contractors, are subject to particular restrictions related to participation in Foreign Government Sponsored or Affiliated Activities, as defined and detailed in United States Department of Energy Order 486.1A. You will be asked to disclose any such participation in the application phase for review by Argonne's Legal Department. All Argonne offers of employment are contingent upon a background check that includes an assessment of criminal conviction history conducted on an individualized and case-by-case basis. Please be advised that Argonne positions require upon hire (or may require in the future) for the individual be to obtain a government access authorization that involves additional background check requirements. Failure to obtain or maintain such government access authorization could result in the withdrawal of a job offer or future termination of employment. Interested in translating science into innovation? Build your career at Argonne. At Argonne, we view the world from a different perspective. Our scientists and engineers conduct world-class research in clean energy, the environment, technology, national security and more. We’re finding creative ways to prepare the world for a better future. To learn more about Argonne's benefits programs, amenities, and other employee programs, visit our main Careers site. To learn more about the exciting science going on at Argonne, visit our Science and Technology page. To request a reasonable accommodation or for other application support, contact us anytime at careers@anl.gov or 630-252-2336.

Salary : $72,879 - $121,465