Scientist I or II / Mass Spectrometry Screening

Make your mark for patients

We are seeking a highly motivated and independent Scientist I or II / Mass Spectrometry Screening to join our Discovery Sciences team at the UCB-Boston (Cambridge) site. This role will support early-stage programs across UCB’s therapeutic areas of interest through designing, executing, and interpretingmass spec-based assays for hit discovery and hit to lead optimization. Please note that this is a lab-based position requiring you to be onsite 5 days/week.

Key Responsibilities

• Design, develop, and execute Affinity Selection Mass Spectrometry (AS‑MS) assays to support small-molecule and peptide screening in collaboration with discovery teams.
• Work as part of a cross‑functional team to develop and deploy mass spec-based screening strategies and communicate results to drive pipeline research programs.
• Generate large screening data sets and collaborate with Data Analytics team to leverage data for hit selection and SAR generation.
• Maintain, troubleshoot, and improve MS instruments and workflows.
• Stay current with advances in mass-spectrometry based technologies and emerging methodologies in the field.
  
  

Required Qualifications

• MS or PhD in Analytical Chemistry, Chemistry, Biochemistry, or related discipline. Recent PhD graduates with strong hands-on AS‑MS experience are encouraged to apply
• Demonstrated expertise in mass spectrometry. Direct experience with AS/MS, MS/MS, and library screening is preferred.
• Prior knowledge of the relevant application area (e.g., discovery screening, protein–ligand interactions, small-molecule analysis)
• Strong analytical thinking, problem‑solving, and scientific communication skills
  
  

Preferred Qualifications

• Experience with developing and prosecuting peptide-based library screening using MS is highly preferred.
• Experience with LC–MS, HRMS, and MS/MS in the context of AS‑MS workflows
• Experience working in a discovery or industry research environment is a plus
• Publications or conference presentations in mass spectrometry or related fields.
  
  

Salary:

This position’s reasonably anticipated base salary range is $99,200 To $130,200 per year. The actual salary offered will consider internal equity and may also vary depending on the candidate’s region, job-related knowledge, skills and experience, among other factors.

Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you!

About Us

UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are over 9.000 people in all four corners of the globe, inspired by patients and driven by science.

Why work with us?

At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equal opportunities to do their best work. We ‘go beyond’ to create value for our patients, and always with a human focus, whether that’s on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential.

At UCB, we’ve embraced a hybrid-first approach to work, bringing teams together in local hubs to foster collaborative curiosity. Unless expressly stated in the description or precluded by the nature of the position, roles are hybrid with 40% of your time spent in the office.

UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable laws.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on EMEA-Reasonable_Accommodation@ucb.com. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.