What are the responsibilities and job description for the Project Scientist - Alzheimer’s Disease & Down Syndrome Research (UCI MIND) position at UC Irvine?
Position Overview
Salary range: The salary range for this position is $76,700 -$201,900. The posted UC salary scales set the minimum pay determined by rank and step at appointment. See Table 37B Represented Project Scientist Series [ REPRESENTED PROJECT SCIENTIST SERIES SALARY SCALE ]. “Off- scale salaries”, i.e. a salary that is higher than the published system-wide salary at the designated rank and step, are offered when necessary to meet competitive conditions.
Application Window
Open date: June 29, 2026
Next review date: Wednesday, Jul 29, 2026 at 11:59pm (Pacific Time)
Apply by this date to ensure full consideration by the committee.
Final date: Wednesday, Jul 29, 2026 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date.
Position Description
This position is for a Project Scientist supporting NIH-funded research projects focused on aging and Alzheimer’s disease in Down syndrome. The Project Scientist will work under the direction of the Principal Investigator and contribute to ongoing collaborative research programs examining neuropathological and cerebrovascular mechanisms underlying Alzheimer’s disease in Down syndrome.
Responsibilities include supporting PI-directed research activities such as project organization, coordination of research workflows, assistance with research project administration and PI-directed grant budgeting activities, tracking project timelines, contributing to progress reports, and assisting with manuscript preparation and grant application development. The Project Scientist will contribute to and coordinate PI-directed research projects and may lead defined components of studies under PI supervision, including research projects to evaluate the contribution of cerebrovascular pathology to the development of Alzheimer disease in the brains of people with Down syndrome. The role includes application of advanced neuropathological methods, including immunohistochemistry, immunofluorescence, digital pathology, statistical analysis, and human brain anatomy expertise. Additional responsibilities include providing technical mentorship and training to research staff, students, and trainees participating in NIH-funded research projects. Required qualifications include excellent written and verbal communication skills, a strong background in neuropathology or neurodegenerative disease research, and a publication record in Alzheimer’s disease or related fields. Expertise in Down syndrome Alzheimer’s disease research is preferred. A PhD in neuroscience, neurobiology, molecular biology, or a related field is required, along with at least 3 years of postdoctoral research experience.
Rank will be determined based on qualifications and experience. Term appointments are based on performance and availability of funding. Candidates are welcome to explain how they have contributed to inclusive excellence in their teaching, research, and service.
The University of California remains fully committed to inclusive excellence and encourages applicants to address how their skills, expertise, and experiences might serve the varied communities of California. Please feel free to include information in any of your application materials relevant to your inclusive excellence work in research, teaching, and service.
Qualifications
Basic qualifications (required at time of application)
The candidate for a title in this series must have earned a doctorate, or its equivalent.
Application Requirements
Document requirements
About UC Irvine
The University of California, Irvine is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC anti-discrimination policy .
As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.
Job location
Irvine, California
Salary range: The salary range for this position is $76,700 -$201,900. The posted UC salary scales set the minimum pay determined by rank and step at appointment. See Table 37B Represented Project Scientist Series [ REPRESENTED PROJECT SCIENTIST SERIES SALARY SCALE ]. “Off- scale salaries”, i.e. a salary that is higher than the published system-wide salary at the designated rank and step, are offered when necessary to meet competitive conditions.
Application Window
Open date: June 29, 2026
Next review date: Wednesday, Jul 29, 2026 at 11:59pm (Pacific Time)
Apply by this date to ensure full consideration by the committee.
Final date: Wednesday, Jul 29, 2026 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date.
Position Description
This position is for a Project Scientist supporting NIH-funded research projects focused on aging and Alzheimer’s disease in Down syndrome. The Project Scientist will work under the direction of the Principal Investigator and contribute to ongoing collaborative research programs examining neuropathological and cerebrovascular mechanisms underlying Alzheimer’s disease in Down syndrome.
Responsibilities include supporting PI-directed research activities such as project organization, coordination of research workflows, assistance with research project administration and PI-directed grant budgeting activities, tracking project timelines, contributing to progress reports, and assisting with manuscript preparation and grant application development. The Project Scientist will contribute to and coordinate PI-directed research projects and may lead defined components of studies under PI supervision, including research projects to evaluate the contribution of cerebrovascular pathology to the development of Alzheimer disease in the brains of people with Down syndrome. The role includes application of advanced neuropathological methods, including immunohistochemistry, immunofluorescence, digital pathology, statistical analysis, and human brain anatomy expertise. Additional responsibilities include providing technical mentorship and training to research staff, students, and trainees participating in NIH-funded research projects. Required qualifications include excellent written and verbal communication skills, a strong background in neuropathology or neurodegenerative disease research, and a publication record in Alzheimer’s disease or related fields. Expertise in Down syndrome Alzheimer’s disease research is preferred. A PhD in neuroscience, neurobiology, molecular biology, or a related field is required, along with at least 3 years of postdoctoral research experience.
Rank will be determined based on qualifications and experience. Term appointments are based on performance and availability of funding. Candidates are welcome to explain how they have contributed to inclusive excellence in their teaching, research, and service.
The University of California remains fully committed to inclusive excellence and encourages applicants to address how their skills, expertise, and experiences might serve the varied communities of California. Please feel free to include information in any of your application materials relevant to your inclusive excellence work in research, teaching, and service.
Qualifications
Basic qualifications (required at time of application)
The candidate for a title in this series must have earned a doctorate, or its equivalent.
Application Requirements
Document requirements
- Curriculum Vitae - Include most recent CV. Ensure the CV includes the Month and Year in which highest degree was conferred.
- Cover Letter (Optional)
- Statement of Research (Optional)
- 3-5 required (contact information only)
About UC Irvine
The University of California, Irvine is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC anti-discrimination policy .
As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.
- “Misconduct” means any violation of the policies or laws governing conduct at the applicant’s previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment or discrimination, as defined by the employer.
- UC Sexual Violence and Sexual Harassment Policy
- UC Anti-Discrimination Policy for Employees, Students and Third Parties
- APM - 035: Affirmative Action and Nondiscrimination in Employment .
Job location
Irvine, California
Salary : $76,700 - $201,900