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Staff Platform Engineer

twistbioscience
South San Francisco, CA Full Time
POSTED ON 10/7/2025
AVAILABLE BEFORE 12/6/2025

Staff Platform Engineer ( Hybride in South San Francisco) 

Job Description

We are seeking an experienced and highly skilled Platform Staff Engineer to join our dynamic team. The ideal candidate will be proficient in Java and Python, with a deep understanding of system architecture, systems integrations, API design, and big data systems such as Amazon EMR. As a Platform Staff Engineer, you will play a crucial role in designing and building scalable, high-performance platforms that support our cutting-edge products and services.

Key Responsibilities:

  • System Architecture & Design: Develop and maintain the architecture of complex systems, ensuring they are scalable, robust, and meet business requirements.
  • Systems Integration: Design and implement integrations between various systems and platforms, ensuring seamless data flow and interoperability.
  • API Design & Development: Create and maintain RESTful APIs, ensuring they are well-documented, secure, and performant.
  • Big Data Systems: Work with big data technologies such as Amazon EMR to process and analyze large datasets, ensuring data is readily available for analytics and decision-making.
  • Code Development & Review: Write clean, maintainable, and efficient code in Java and Python. Conduct code reviews to ensure adherence to best practices and quality standards.
  • Collaboration & Leadership: Collaborate with cross-functional teams, including product managers, data scientists, and other engineers, to deliver high-quality solutions. Provide technical leadership and mentorship to junior engineers.
  • Performance Optimization: Continuously monitor and optimize system performance, identifying and addressing bottlenecks and performance issues.
  • Security & Compliance: Ensure that all systems and integrations adhere to security best practices and comply with relevant regulations and standards.

Qualifications:

  • Educational Background: Bachelor’s or Master’s degree in Computer Science, Engineering, or a related field.
  • Experience: Minimum of 8 years of experience in software engineering, with a focus on platform engineering, system architecture, and systems integration.
  • Technical Skills:
  • Proficient in Java and Python.
  • Extensive experience with system architecture and design.

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.

The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.

San Francisco Bay Area Pay Range

$185,709 - $220,500 USD

Salary : $185,709 - $220,500

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