Demo

Manufacturing Associate II

TScan Therapeutics
Waltham, MA Full Time
POSTED ON 4/18/2026
AVAILABLE BEFORE 5/17/2026
Position Summary

TScan Therapeutics is a clinical-stage biotech seeking to revolutionize life-changing therapeutics for patients by identifying novel T cells and epitopes. We are hiring Manufacturing Associate I-II to support and drive our internal Cell Therapy Manufacturing. These positions will be based in our cGMP Manufacturing site in Waltham, MA.

The ideal candidates have demonstrated experience in cell therapy or biologics manufacturing, have robust knowledge of cGMPs, and enjoy fast-paced, collaborative environments. A team player with a sense of urgency will thrive in this role.

This role is on-site and will follow a shift schedule. Roles will train on a Monday – Friday schedule before transitioning to rotating day shifts (including weekends) for operations.

Responsibilities

Responsibilities include, but are not limited to:

  • Execute cGMP manufacturing of TScan cell therapy products while adhering to cGMPs, SOPs, compliance/regulatory mandates, safety procedures, and quality requirement
  • Accurately complete appropriate production documentation for all processing steps
  • Maintain cleanliness and orderliness of process area, ensuring production area is stocked with supplies
  • Participate in batch record review, procedure revisions, and bill of materials
  • Utilize manufacturing knowledge to improve process operations and assist in the identification and implementation of continuous improvement opportunities
  • Assist in the creation and revision of manufacturing documentation
  • Maintain equipment operation through responsive troubleshooting, repairs, and following operation guidelines
  • Document all production efforts in appropriate logs, forms, reports, and databases
  • Identify and assist in the corrective actions of processing-related issues

Requirements

  • High School Diploma or GED required, at minimum; Bachelor’s degree preferred
  • 2-4 years of experience in cGMP manufacturing in the biotech or pharmaceutical industry
    • Prior cell therapy manufacturing experience highly preferred, advanced biologics required in lieu of CT
  • Must be able to read, write, and speak English fluently
  • Experience in reviewing and creating controlled documents
  • After safety training, must be able to perform required tasks in a fully compliant manner
  • Must be able to lift and transport (using carts or wheelies) packages weighing up to 50 pounds
  • Extensive walking throughout the facility will be required
  • Demonstrated success in delivery of key milestones against tight timelines
  • Ability to prioritize, manage time well, multitask, troubleshoot
  • Must be able to use a company-issued computer and have at least intermediate skills in Microsoft Word, Excel, Outlook, and PowerPoint programs needed to perform job
About TScan

TScan Therapeutics was founded in 2018 by a small group of scientists led by Dr. Stephen Elledge (Harvard Medical School/HHMI). TScan is discovering and developing novel TCR-engineered T cell therapies for the treatment of cancer. TScan’s discovery platform is centered around a breakthrough technology that enables the rapid, comprehensive, and genome-wide identification of the peptide antigen targets of T cell receptors. This technology greatly enhances our ability to understand the specific antigens that drive important disease processes, including tumor cell recognition by the immune system, self-reactivity in autoimmune disorders, and acquired immunity in infectious disease. TScan is using the platform in oncology to discover new TCR/target pairs and to rapidly move novel TCRs into clinical development.

Do YOU have the anatomy of a TScanner?

Our talented, compassionate and intelligent team is what makes TScan a great place to work. Our brand new offices with approximately 40,000 square feet of premium lab and office space is an environment that supports innovation, camaraderie and professionalism. We are driven, passionate, fun, flexible and team oriented. Sound like you? Apply today.

EEO Statement

TScan is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate. TScan provides reasonable accommodations to qualified applicants and employees with disabilities. To begin an interactive dialogue with TScan regarding a reasonable accommodation in connection with the hiring process and/or to perform the responsibilities of the position for which the applicant has applied, please contact the recruiter.

Pay Range: $95,000 – $122,500

Pay Transparency

TScan Therapeutics’ pay ranges are established based on external market data from third-party compensation surveys and our internal benchmarking. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Individual compensation within this range is commensurate with a candidate’s specific qualifications, including education, overall experience, relevant experience, and specific skills. We strive to ensure that compensation is competitive, equitable, and aligned with the value each TScanner brings to the role.

Recruitment & Staffing Agencies

TScan Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to TScan Therapeutics or its employees is strictly prohibited unless contacted directly by TScan Therapeutics’ internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of TScan Therapeutics, and TScan Therapeutics will not owe any referral or other fees with respect thereto.

Salary : $95,000 - $122,500

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