Senior Program Manager, Commercial Operations

Role Overview

The Program Manager, Commercial Operations will drive disciplined execution, operational readiness, and process excellence across commercial launch program. This role sits at the center of cross-functional coordination—ensuring teams are aligned, risks are surfaced early, timelines are maintained, and launch-critical processes are mapped, optimized, and repeatable.

The ideal candidate brings experience supporting biotech/pharma commercial launches, paired with strong program management, operational excellence, and process-improvement capabilities. This role is designed for someone who thrives in structured planning, cross-functional orchestration, and building scalable frameworks in a fast-moving, high-growth environment.

Responsibilities:

Commercial Launch Program Management

• Maintain the integrated commercial launch plan, tracking timelines, dependencies, and critical-path activities across Commercial, Medical, Market Access, Patient Services, Supply Chain, Quality, and Finance.
• Drive cross-functional launch meetings: set agendas, capture decisions, track action items, and ensure accountable follow-through.
• Prepare materials for commercial readiness reviews, governance meetings, and executive updates.

Operational Excellence & Process Optimization

• Map, document, and optimize cross-functional launch processes, identifying bottlenecks and opportunities for standardization.
• Build and maintain repeatable operating mechanisms (templates, trackers, dashboards, workflows, RACI matrices).
• Support continuous improvement by introducing tools, metrics, and operational discipline to strengthen execution quality.

Risk Management & Governance

• Identify and mitigate risks, dependencies, and resource constraints impacting launch readiness.
• Ensure alignment between functional plans and enterprise-level objectives, escalating issues when necessary.
• Maintain structured documentation (decision logs, RAID logs, governance summaries) to ensure transparency.

Cross-Functional Alignment & Communication

• Translate high-level strategic goals into executable workplans with clear owners, timelines, and measurable outcomes.
• Serve as the central coordinator connecting Commercial with supporting functions (Regulatory, Quality, Supply Chain, Medical Affairs, Finance).
• Enable consistent communication and ensure all teams have access to up-to-date timelines, plans, and reference materials. Post-Launch Optimization
• Support post-launch retrospectives by gathering lessons learned and integrating improvements into future launch frameworks. • Partner with functional leads to refine SOPs, playbooks, and operational processes for future programs

Requirements

• Bachelor’s degree required; PMP, CAPM, Lean/Six Sigma, or program management training a strong plus.
• 3–5 years of experience supporting biotech/pharma commercial launches (required).
• Experience in program management, operational excellence, or process optimization within life sciences.
• Strong ability to manage multiple parallel workstreams, synthesize complex information, and drive structured execution.
• Excellent communication, facilitation, and follow-through skills; effective at influencing without authority.
• Proficiency with project management and workflow tools (Smartsheet, MS Project, Asana, Monday.com, Miro, etc.).
• Comfort working in a dynamic lean biotech environment with evolving priorities and accelerated timelines.