Senior Accounting Manager/Associate Director

Location: South San Francisco, CA – Hybrid, with the ability to be in office 2-3 days per week

Position Summary:

The Senior Accounting Manager/Associate Director will be a hands-on accounting leader responsible for a high-quality, on-time close and scalable accounting processes as we grow. You’ll partner closely with the Controller and cross-functional leaders to ensure accurate financial reporting, strong controls, and audit readiness without slowing the pace of the business.

Key Responsibilities include but are not limited to:

• Lead preparation of the monthly reporting package to the leadership team (coordinate with appropriate parties)
• Manage the year end audit requirements with external auditors as well as quarter end audit reviews and ensure internal controls are well documented
• Own key elements of the monthly/quarterly/year-end close (journal entries, accruals, allocations, reconciliations, flux analysis) with a high bar for accuracy and speed
• Drive close process discipline: timelines, checklists, documentation, and continuous improvement (reduce cycle time; increase quality)
• Oversee core GL operations including account reconciliations, subledger tie-outs, and balance sheet integrity
• Strengthen internal controls: design/implement policies, controls, and review procedures appropriate for a scaling biotech
• Biotech-specific accounting (as applicable): R&D and clinical trial accounting (CRO/vendor accruals), prepaids, payroll-related entries, equity administration accounting/ASC 718 support, and related disclosures
• Systems & process scaling: improve ERP workflows (e.g., NetSuite or similar), integrations, and reporting; build repeatable processes as headcount/program count grows

Required Qualifications:

• Bachelor’s degree in Accounting, Finance, or related field
• 10 years of progressive accounting experience (biotech/pharma strongly preferred)
• Public accounting experience, plus relevant industry experience
• Demonstrated ownership of a fast, accurate financial, close and strong reconciliation discipline
• Solid technical accounting foundation (US GAAP); ability to research and document positions
• Experience supporting audits and working effectively with external advisors
• High proficiency with ERPs and Excel; ability to improve workflows and controls

Preferred Qualifications:

• Experience in clinical-stage companies
• NetSuite experience (or similar ERP implementation/optimization)
• Experience with equity accounting (ASC 718), 409A-related support, and/or purchase accounting exposure
• Track record of building scalable processes in a lean environment.

Compensation: $160,000 - $175,000, plus Discretionary Bonus.

TRexBio is a clinical stage biotechnology company leveraging cutting edge computational biology tools, a focus on human tissue, and expertise in immunobiology to develop revolutionary therapeutics for inflammatory diseases. Our powerful ‘deep biology’ discovery engine maps human tissue Treg behavior to disease processes, allowing us to identify and characterize novel targets for therapeutic intervention. Leveraging this platform, we are building a broad portfolio of novel therapies that modulate the immune system to restore human tissue immune homeostasis.

Our Culture:

At TRexBio, you will have the opportunity to work with amazingly smart humans who strive to make the world a better place. In addition to our team-centric culture, we believe that your individual creativity will help us to be our best. Our staff happy hours, organized by our Culture Club, bring us all together in creative and social activities. Our colleagues admire and respect one another. We celebrate our wins, update company news and acknowledge each other’s achievement weekly and monthly at all company meetings that celebrate our work and our people.

TRexBio is proud to be an AA/EEO employer and all qualified candidates will receive consideration without regard to characteristics protected by applicable local, state, or federal law, such as race, color, sex, age, religion, national origin, physical or mental disability, pregnancy, marital status, veteran or military status, genetic information, or sexual orientation.