What are the responsibilities and job description for the Senior Construction Project Manager position at Thesis Pharmacy?
Senior Construction Project Manager
North Texas | Full-Time | On-Site
The Opportunity
We are building two pharmaceutical manufacturing facilities in North Texas, including ISO 7 / ISO 8 cleanrooms, pharmaceutical-grade HVAC systems, clean utilities, and highly regulated production environments.
This is not a traditional commercial construction role.
We are seeking a hands-on Construction Project Manager with direct experience in regulated or technically complex facility construction who can own this project from pre-construction through commissioning and closeout. The ideal candidate brings pharmaceutical, cleanroom, biotech or regulated industrial facility experience and discipline to deliver a cGMP compliant building on schedule, within budget and for regulatory inspection from Day 1. After project completion, this role can transition into a long-term Facilities Manager leadership position overseeing ongoing operations, infrastructure, facilities maintenance, and future expansion projects. This role is ideal for someone who wants long-term ownership inside a growing organization.
What You’ll Own
Pre-Construction & Planning
- Lead constructability reviews, value engineering and phasing plans for a cGMP facility build.
- Collaborate with architects, MEP engineers, cleanroom vendors and the owner’s team to finalize design documents aligned with pharmaceutical regulatory requirements.
- Establish project budget baseline, schedule and risk register prior to start of construction
- Evaluate, select and contract specialty subcontractors with demonstrated experience in regulated or environments.
Construction Phase
- Serve as the owner-side project manager throughout the full construction lifecycle.
- Manage day-to-day field execution, subcontractor performance, RFIs, submittals, change orders, and schedule compliance
- Oversee installation and coordination of cGMP-critical building systems, including:
- Pharmaceutical-grade HVAC with HEPA filtration and pressure-differential controls
- ISO 8 cleanroom envelope, finishes, and pass-throughs
- Clean utilities: purified water (PW), clean steam, and clean compressed air/dry nitrogen (as applicable)
- Building automation system (BAS) for environmental monitoring
- Electrical systems, lighting, and emergency power for production areas
- Maintain audit-ready project documentation throughout construction, including daily reports, inspection records, and commissioning prerequisites
- Manage owner’s budget and forecast with rigorous cost-control discipline; approve pay applications and change orders
Commissioning, Qualification & Closeout
- Coordinate with the owner’s commissioning and qualification (C&Q) team to develop Construction Turnover Packages (CTPs) and support IQ/OQ prerequisites
- Oversee systems commissioning, punch-list resolution, and certificate of occupancy process
- Deliver a complete project closeout package including as-builts, O&M manuals, spare parts, and regulatory-ready documentation
Required Qualifications
- 5 years of construction project management experience, with at least 2 years on pharmaceutical, biotech, cleanroom, semiconductor, or other regulated / technically complex facility projects
- Demonstrated experience managing cGMP-critical building systems: HVAC, clean utilities, BAS, and classified environments
- Direct experience managing MEP coordination on technically complex projects
- Strong budget ownership and cost-control discipline on projects ranging from $5M–$20M
- Proven subcontractor selection, contracting, and performance management skills
- Proficiency with Procore, Buildertrend, or equivalent construction management software; Microsoft Project or Primavera P6 for scheduling
- Strong written and verbal communication; ability to produce clear documentation for owner, design team, and regulatory purposes
- Ability to work independently in a lean, fast-paced environment with high ownership
Strongly Preferred
- Direct cGMP pharmaceutical or biotech facility construction experience (greenfield or bownfield)
- Hands-on experience with ISO-classified cleanrooms (ISO 7 or ISO 8)
- Experience participating in commissioning, qualification (IQ/OQ/PQ) or facility validation processes
- Knowledge of ISPE baseline guides or similar pharmaceutical facility design standards.
- Bachelor’s degree in Construction Management, Mechanical, Civil or Architectural Engineering or a related field.
- PMP, CCM, or OSHA 30 certification
Why This Role
- Build pharmaceutical facility from the ground up with full ownership over every phase
- Direct access to company leadership and decision-makers throughout the project
- Contribute to bringing new pharmaceutical products to market
- Opportunity to grow into a Long-term Facilities & Engineering Management role post construction
- Competitive compensation and full benefits package
Compensation & Benefits
- Competitive salary based on experience
- Medical, Dental, and Vision insurance
- Paid Time Off and paid holidays
- Career advancement opportunities
- High-impact leadership role with long-term growth potential