Senior Staff Manufacturing Engineer

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Able to lift 40 lbs. without assistance, Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Cleanroom: no hair products, jewelry, makeup, nail polish, perfume, exposed piercings, facial hair etc... allowed, Laboratory Setting, Loud Noises (Equipment/Machinery), Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.), Strong Odors (chemical, lubricants, biological products etc.)

About Thermo Fisher Scientific

At Thermo Fisher Scientific, you’ll do meaningful work that makes a real-world impact. Our Mission is to enable our customers to make the world healthier, cleaner and safer.

We support our colleagues with the tools, resources, and opportunities to grow their careers while advancing solutions that address global challenges—from improving human health to protecting our environment.

What You’ll Do

As a Sr. Staff Manufacturing Engineer, you will lead and contribute to complex technical initiatives that support advanced manufacturing operations. This role plays a critical part in driving innovation, operational excellence, and compliance within a regulated environment.

You will work with automation systems, process control platforms, and manufacturing technologies while partnering across functions to design, implement, and optimize processes—from concept through validation and handover.

Key Responsibilities

• Lead and contribute to engineering projects involving manufacturing equipment, automation systems, and process improvements
• Design and implement solutions to improve process efficiency, reliability, and compliance
• Support installation, qualification, and validation of manufacturing equipment and systems
• Collaborate with R&D, Quality, and Operations to resolve technical challenges and support production needs
• Develop and maintain engineering and validation documentation (e.g., URS, FRS, IOQ protocols)
• Ensure adherence to cGMP requirements and data integrity standards
• Support capital projects, including planning, execution, and budget tracking
• Troubleshoot and resolve complex equipment, automation, and process issues
• Provide technical guidance and mentorship to junior engineers
  
  

Minimum Qualifications

• Advanced degree with 6 years of experience, or bachelor’s degree with 8 years of experience in pharmaceutical, biotech, or other regulated manufacturing environments
• Degree in Engineering (Chemical, Mechanical, Electrical, Automation, or related field preferred)
• Experience with manufacturing automation and control systems (e.g., PLCs, SCADA, or DCS platforms)
• Experience working in cGMP-regulated environments
• Demonstrated experience implementing process improvements in a manufacturing setting
• Experience with engineering documentation and validation practices
• Strong problem-solving and analytical skills
• Ability to collaborate effectively across cross-functional teams
• Clear written and verbal communication skills
  
  

Preferred Qualifications

• Experience with Rockwell/Allen-Bradley, FactoryTalk, or DeltaV systems
• Experience with capital project execution in a manufacturing environment
• Familiarity with AutoCAD, MS Project, or Visio
• Experience supporting audit readiness and data integrity practices
• Demonstrated ability to mentor or guide other engineers
  
  

Why Join Thermo Fisher Scientific?

You’ll be part of a team that values innovation, integrity, intensity, and involvement, where your work directly contributes to advancing science and improving lives.

Compensation And Benefits

The salary range estimated for this position based in California is $143,000.00–$214,475.00.

This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:

• A choice of national medical and dental plans, and a national vision plan, including health incentive programs
• Employee assistance and family support programs, including commuter benefits and tuition reimbursement
• At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
• Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
• Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
  
  

For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards