What are the responsibilities and job description for the Postdoc position in RNA biology in the Höpfler lab (CRG Barcelona) position at The RNA Society?
Posted on: May 13, 2026
Centre for Genomic Regulation (CRG)
The Höpfler lab is looking for a postdoctoral researcher to lead a project in the field of RNA biology and gene regulation with a strong interest in driving development of sequencing methods to identify mRNA decay substrates and decipher degradation mechanisms.
The role
The successful candidate will join the Dynamics of Protein Synthesis and RNA Decay Group. Their work will address an exciting question in gene regulation: how cells dynamically control the stability of messenger RNAs by selective degradation during protein synthesis by the ribosome. The lab studies this problem in the context of both fundamental molecular mechanisms and disease-related regulation.
Responsibilities
The position will be a chance to join a young, ambitious and curiosity-driven lab at the CRG, one of Europe’s prime institutes for molecular life sciences, surrounded by the dynamic Barcelona research environment. The project is embedded in the ERC-funded DECODE-PMD project to better understand peptide-mediated mRNA decay (PMD). Key responsibilities include:
We are particularly interested in candidates with a hybrid wet lab bioinformatics background with a track record in RNA biology or gene regulation, but we will consider applications with related expertise. Experience with sequencing approaches to study RNA turnover or with massively parallel reporter assays (MPRAs) will be beneficial. We value strong interpersonal skills, curiosity, critical thinking as well as organizational skills.
The Offer – Working Conditions
An initial contract will be offered for 2 years (renewable), salary will be commensurate with qualifications and consistent with our pay scales. We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities.
We offer and promote a diverse and inclusive environment and welcome applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity. The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.
Target Start date: October 2026 (flexible).
Application Procedure
Detailed Information Can Be Found On The CRG Career Site. All Applications Must Be Submitted Directly Through The Career Site Portal (evaluations From 31/05/2026 Until The Position Is Filled)
https://recruitment.crg.eu/content/jobs/position/postdoc-dynamics-protein-synthesis-and-rna-decay-lab-0
https://recruitment.crg.eu/content/jobs/open-positions
Contact: Markus Höpfler markus.hopfler@crg.eu
https://www.crg.eu/en/programmes-groups/hopfler-lab
View All Job Postings >>
Centre for Genomic Regulation (CRG)
The Höpfler lab is looking for a postdoctoral researcher to lead a project in the field of RNA biology and gene regulation with a strong interest in driving development of sequencing methods to identify mRNA decay substrates and decipher degradation mechanisms.
The role
The successful candidate will join the Dynamics of Protein Synthesis and RNA Decay Group. Their work will address an exciting question in gene regulation: how cells dynamically control the stability of messenger RNAs by selective degradation during protein synthesis by the ribosome. The lab studies this problem in the context of both fundamental molecular mechanisms and disease-related regulation.
Responsibilities
The position will be a chance to join a young, ambitious and curiosity-driven lab at the CRG, one of Europe’s prime institutes for molecular life sciences, surrounded by the dynamic Barcelona research environment. The project is embedded in the ERC-funded DECODE-PMD project to better understand peptide-mediated mRNA decay (PMD). Key responsibilities include:
- Development of sequencing & MPRA approaches to identify PMD substrates
- Bioinformatic data analysis and visualization
- Identification and mechanistic characterization of PMD candidate substrates
- Presentation of data at international conferences and manuscript preparation
- Leading and managing international collaborations
- Active participation in lab meetings and contribution to a culture of technical excellence and scientific curiosity
We are particularly interested in candidates with a hybrid wet lab bioinformatics background with a track record in RNA biology or gene regulation, but we will consider applications with related expertise. Experience with sequencing approaches to study RNA turnover or with massively parallel reporter assays (MPRAs) will be beneficial. We value strong interpersonal skills, curiosity, critical thinking as well as organizational skills.
The Offer – Working Conditions
An initial contract will be offered for 2 years (renewable), salary will be commensurate with qualifications and consistent with our pay scales. We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities.
We offer and promote a diverse and inclusive environment and welcome applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity. The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.
Target Start date: October 2026 (flexible).
Application Procedure
Detailed Information Can Be Found On The CRG Career Site. All Applications Must Be Submitted Directly Through The Career Site Portal (evaluations From 31/05/2026 Until The Position Is Filled)
https://recruitment.crg.eu/content/jobs/position/postdoc-dynamics-protein-synthesis-and-rna-decay-lab-0
https://recruitment.crg.eu/content/jobs/open-positions
Contact: Markus Höpfler markus.hopfler@crg.eu
https://www.crg.eu/en/programmes-groups/hopfler-lab
View All Job Postings >>