What are the responsibilities and job description for the Biologist II/III (LCMS Bioanalysis) position at The Fountain Group?
Details for the position are as follows:
- Rate: Biologist II rate is $41 an hour Biologist III rate is $49 an hour.
- Location: Worcester, MA -100% onsite
- 6-month contract to start with the possibility of extension or conversion depending on performance and business needs.
- Hours: Monday - Friday 9-5
- The Quantitative, Translational ADME Sciences (QTAS) department at Client is seeking a highly motivated and energetic bioanalytical scientist to join the biologics bioanalysis, characterization, and proteomics (BBCP) group. The primary responsibility of this position is to support LC-MS (liquid chromatography-mass spectrometry)-based bioanalysis and method development for biologic entities, such as monoclonal antibodies, multi-specific antibodies, antibody-drug conjugates (ADCs), and other Client modalities. The successful candidate will have experience in optimizing and implementing hybrid LC-MS-based bioanalytical methods to support non-regulated preclinical PK and TK studies. Responsibilities include routine sample preparation, method development, instrument maintenance, data analysis, report writing, and presenting data at internal and external meetings.
- Perform affinity purification and digestion of biological therapeutics (including but not limited to monoclonal and bispecific antibodies, antibody drug conjugates, antibody-siRNA conjugates, and fusion proteins) from biological matrices manually or using automation systems.
- Operate and maintain LC/MS instruments to generate high-quality experimental data.
- Optimize and develop LC/MS methods to meet assay specificity and sensitivity requirements.
- Analyze data and maintain detailed, accurate and comprehensive study documentation in electronic laboratory notebooks.
- Communicate data interpretation internally and externally.
- Degree in chemistry, pharmacology or other related fields. BS with 5 years or MS with 2 years in a pharmaceutical industry setting with a focus on mass spectrometry. Prior industry experience in drug discovery/development is highly desired.
- Hands-on experience with QQQ (SCIEX) Mass Spectrometer is required, additional experience with qTOF (Agilent, Bruker, SCIEX) and/or Orbitrap (Thermo) mass spectrometers is a plus.
- Hands-on experience with biologics bioanalysis is highly desired, additional experience with oligonucleotide analysis is a plus.
- Hands-on experience with immuno-affinity purification and automation systems (e.g., TECAN, AssayMap Bravo or Hamilton) is highly desired.
- Highly motivated, self-driven and results-oriented with excellent communication and presentation skills; capable of working both as a team player and individual contributor.
Salary : $41 - $49