Scientist I/II, Bioanalytical (LC-MS)

Your experience includes… 

• PhD in Analytical Chemistry or related discipline e.g., Biochemistry, Biotechnology or Pharmaceutical Science, with 0-3 years of industry experience in biotech, pharmaceutical, and/or CROs. Postdoc experience is a plus.
• Hands-on Experience in LC-MS based bioanalysis of proteins, oligos or small molecules in biological matrix is required.
• In-depth scientific knowledge and hands on technical expertise on LC-MS, LC-MS/MS, and chromatography methodologies and instrumentation is required.
• Proficiency of using Sciex Triple Quadrupole LC-MS/MS system or Thermo Orbitrap mass spectrometers such as Q Exactive series or Exploris series.
• Experience with lab automation technologies is a plus.

You are interested in… 

• Develop, optimize, and validate bioanalytical methods to measure proteins, oligos, and lipids in biological samples, including cells, biofluids, and tissues, to support the development of discovery, preclinical and clinical programs.
• Design and execute experiments from sample preparation, LC-MS/MS operation to data analysis & interpretation.
• Guide CROs for method transfer CROs and serve as technical expert for method trouble shooting.
• Write internal assay protocols, ROPs, qualification plans, and sample analysis reports.
• Provide maintenance, quality control and troubleshooting of LC-MS systems.

About you: 

We are seeking a highly motivated bioanalytical scientist to fulfil a Scientist role in our DMPK group. The candidate will be responsible for developing and employing LC-MS methods to characterize and quantitate proteins, oligos and lipid in cells, blood and tissues to support discovery, preclinical, and clinical programs for a variety of therapeutic indications. The ideal candidate must have excellent communication skills and is willing to work in a highly dynamic and fast-paced work.  

Tessera employees are creative and collaborative problem solvers. They have a strong sense of integrity and unwavering commitment to scientific excellence. 

Meet your Manager:

All inquiries regarding the posted position should be directed to the Talent Partner (see below). Interested individuals must apply directly to be considered for the opening. 

Gang Sun, PhD - Executive Director, DMPK/Bioanalytical

Dr. Gang Sun has over 17 years of experience in DMPK and Bioanalyticals. Dr. Sun has worked with diverse drug modalities, including small molecules, proteins, oligos, and mRNA, across various therapeutic areas such as oncology, immunology, and gene editing. Dr. Sun has actively contributed to the support of discovery, preclinical, and clinical programs. He currently leads a multidisciplinary team at Tessera Therapeutics, where he oversees DMPK, bioanalytical, clinical pharmacology, biomarker, and ADA support for the development of Gene Writing and Rewriting Therapeutics. Prior to joining Tessera Therapeutics, Dr. Sun held positions at Translate Bio, Corbus Pharmaceuticals, Merrimack Pharmaceuticals, Merck & Co., and Covance. His academic credentials include a Ph.D. in Chemistry from Peking University, an M.S. from Qingdao University of Science and Technology, and a B.S. from Qingdao University. 

Meet our Leadership Team and Board of Directors 

Meet your Talent Partner:

Ben Hoogheem – Senior Director, Head of Talent Management

As Head of Talent Management at Tessera Therapeutics, Ben leads Tessera’s talent strategy across talent acquisition, performance management, and talent mobility.

Ben began his career as an in vivo Pharmacologist, which gave him a lasting appreciation for the rigor, creativity, and collaboration that drive scientific discovery. That foundation continues to shape how he helps build organizations designed to enable science thrive.

Ben is focused on aligning exceptional people with bold science – creating the structure, clarity, and culture that empower teams to scale effectively and achieve meaningful impact.

Compensation:

The stated base salary range represents Tessera’s good-faith estimate for this role. Actual compensation will be determined based on a number of factors, including but not limited to individual qualifications, years of relevant experience, internal compensation alignment, and external market data.

Tessera offers a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness, and financial security of our employees and their families. Benefits currently include group medical, vision, and dental coverage; group life and disability insurance; a 401(k) plan with company contribution; tuition reimbursement; and more.

This position is also eligible for an annual incentive bonus and equity grants as part of Tessera’s total rewards program.

Per Year Salary Range: $109,000 - $143,000

Company Summary:

Tessera Therapeutics is pioneering Gene Writing™— a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy.

More about Tessera Therapeutics:

Tessera is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, marital status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate. Tessera provides reasonable accommodations to qualified applicants and employees with disabilities. To begin an interactive dialogue with Tessera regarding a reasonable accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied, please contact the recruiter or Accommodations@tesseratx.com

Recruitment & Staffing Agencies:  Tessera Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Tessera Therapeutics or its employees is strictly prohibited unless contacted directly by Tessera Therapeutics’ internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Tessera Therapeutics, and Tessera Therapeutics will not owe any referral or other fees with respect thereto.