What are the responsibilities and job description for the In-Vivo Research Associate position at Terasaki Institute for Biomedical Innovation?
We seek a highly motivated Research Associate to join our team, focusing on in vivo studies with small animals, including surgical procedures, animal care, sample processing, and histology. The ideal candidate will have hands-on experience in rodent handling, in vivo techniques, and histological methods. This role requires meticulous attention to detail, strong organizational skills, and a commitment to animal welfare.
1. In Vivo Biomaterials Testing
- Perform small animal surgeries (e.g., implant/biomaterials/tumor implantation, catheterization, organ-specific procedures) and post-operative care.
- Administer test articles via routes such as IV, IP, SC, PO, surgically and monitor clinical outcomes.
- Conduct blood/tissue collection, pharmacokinetic (PK) and pharmacodynamic (PD) sampling, and necropsy.
- Maintain accurate records of animal health, experimental data, and regulatory documentation.
2. Histology & Sample Processing
- Process, embed, and section FFPE and frozen tissues using microtomes/cryostats.
- Perform histological staining (H&E, IHC, IF, special stains) and optimize protocols.
- Support advanced techniques (e.g., RNAscope, spatial omics) as needed.
- Manage tissue inventories and digital pathology tools for image analysis.
3. Laboratory Operations
- Prepare reagents, maintain equipment, and ensure compliance with SOPs.
- Collaborate with cross-functional teams to support study design and data analysis.
- Train junior staff on in vivo and histological techniques.
4. Compliance
- Adhere to AAALAC, OLAW, IACUC, and institutional animal welfare guidelines.
- Follow OSHA safety standards and HIPAA regulations for data confidentiality.
Qualifications
- Education:
- BS/BA in Biology, Animal Science, or related field 2 years of in vivo/histology experience
- OR MSc in a relevant discipline hands-on lab experience.
- Technical Skills:
- Proficiency in rodent handling, dosing, and surgical techniques.
- Expertise in histology (sectioning, staining, tissue processing).
- Familiarity with data analysis software (e.g., GraphPad, Excel).
- Certifications (Preferred):
- AALAS certification (LAT/LATG) or histotechnology (HT/HTL).
- Soft Skills:
- Strong communication, teamwork, and problem-solving abilities.
- Ability to multitask in a fast-paced environment.
Preferred Qualifications
- Experience with tissue perfusion, molecular assays (ELISA, PCR), or 3D cell culture/organoids.
- Knowledge of Good Laboratory Practices (GLP).
- Exposure to digital pathology platforms (e.g., HALO, Visiopharm).
Work Environment
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- Laboratory setting with exposure to biological specimens and chemicals.
- Physical demands: Standing for extended periods, lifting up to 25 lbs.
- Occasional weekend/holiday work for time-sensitive studies.
- Key Responsibilities
Applicants must be authorized to work for ANY employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.
Join our interdisciplinary environment to accelerate scientific and technical advancements and contribute to groundbreaking research in in vivo. Your exceptional communication skills, hands-on expertise, and collaborative spirit will play a pivotal role in expanding the horizons.
The duties and responsibilities described are not a comprehensive list and that additional tasks may be assigned to the employee from time to time; or the scope of the job may change as necessitated by business demands.
TIBI is committed to promoting diversity and equal employment opportunities. We champion affirmative action to provide fair opportunities for underrepresented minorities, women, individuals with disabilities, and covered veterans. All qualified applicants will receive consideration regardless of race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status.
Salary : $34 - $38