Demo

Senior Data Scientist, AI RWD

tempus
CO Full Time
POSTED ON 1/11/2026
AVAILABLE BEFORE 2/9/2026
Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. What you’ll do: Design and implement comprehensive evaluation strategies for AI models, including both offline and online (production) settings. Conduct statistical analyses and hypothesis testing to assess model accuracy, precision, recall, F1 score, ROC-AUC, and other relevant performance metrics. Collaborate with clinical data labeling teams, ML engineers and data scientists to define validation datasets, ground truth standards, and performance benchmarks. Analyze model outputs to identify strengths, weaknesses, and potential biases, and provide actionable recommendations for improvement. Develop and maintain metrics, dashboards, and reports to monitor model performance, drift, and stability over time. Communicate findings and recommendations to technical and non-technical stakeholders through clear visualizations and presentations. Develop and maintain documentation and metrics for data quality, profiling results, and value assessments to support transparency and continuous improvement. Qualifications: Bachelor’s or Master’s degree in Computer Science, Data Science, Statistics, Mathematics, Engineering, or a related field. 4 years of experience in data science or machine learning, with a focus on model evaluation and validation. Strong command of statistical analysis and hypothesis testing. Proficiency in Python and/or R, with experience using ML libraries such as scikit-learn, TensorFlow, PyTorch, or similar. Familiarity with model monitoring tools and MLOps platforms is a plus. Experience with data visualization tools (e.g., matplotlib, seaborn, Plotly, Tableau) to communicate model performance is a plus. Excellent problem-solving skills and attention to detail. Strong communication skills, with the ability to explain complex technical concepts to diverse audiences. Experience working in a collaborative, cross-functional team environment. CHI: $100,000-$160,000 USD NYC/SF: $115,000-$175,000 USD The expected salary range above is applicable if the role is performed from Illinois and may vary for other locations (California, Colorado, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position. We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. Tempus was founded in August of 2015 by Eric Lefkofsky, after his wife was diagnosed with Breast Cancer. Shortly after he founded the company in an effort to bring the power of technology and artificial intelligence to cancer care, he convinced Ryan Fukushima to join as the company’s first employee. Ryan and Eric began assembling a world class team, focused on building the first version of a platform capable of ingesting real time healthcare data in an effort to personalize diagnostics. We built the platform for oncology and have expanded it to neuropsychiatry, cardiology, infectious disease (through COVID), and radiology. Despite our rapid growth, our mission remains the same—to help make sure patients are on the right drug at the right time, so they can live longer and healthier lives. We’re looking for people who can change the world. Who question the status quo and don’t shy away from tough problems. For the builders who are never done building and the learners who are never done learning. We’re looking for passionate people with undying curiosity. Those who want to attack one of the most challenging problems mankind has ever faced. Head on.

Salary.com Estimation for Senior Data Scientist, AI RWD in CO
$114,747 to $142,417
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