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Vice President and Head of Business Development

SystImmune
Princeton, NJ Full Time
POSTED ON 10/30/2025 CLOSED ON 1/9/2026

What are the responsibilities and job description for the Vice President and Head of Business Development position at SystImmune?

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.

As the Vice President and Head of Business Development, you will be a key driver in shaping SystImmune’s growth trajectory. Your strategic vision, leadership, and ability to develop our portfolio strategy and forge impactful partnerships will directly impact our clinical asset progress. This role combines business acumen, scientific understanding, and team management to unlock the full potential of our technology platforms and pipeline. You will report directly to the CEO and partner closely with R&D, Finance, and Manufacturing both at SystImmune and its affiliate in China.

Key Responsibilities

  • Business Development Strategy
    • Develop and execute a comprehensive business development strategy aligned with SystImmune’s scientific, strategic, and financing plans
    • Identify licensing, partnership, and collaboration opportunities to accelerate clinical asset development
    • Collaborate closely with the scientific team to define and deliver key data packages and lead all scientific due diligence process by potential partners
    • Develop proposed deal architecture and terms, and lead negotiations of term sheets and agreements with potential partners in collaboration with legal and finance
  • Commercial assessment, competitive landscape, and portfolio strategy:
    • Work closely with R&D to formulate company’s portfolio strategy based on the commercial assessment, scientific data, competitive landscape, market insights, and fit with company’s long-term strategy
    • Oversee and be accountable for commercial assessment to support portfolio decisions and prioritization of portfolio, including but not limited to commercial forecast
    • Develop initial target opportunity profile, build product differentiation hypothesis, and support product development strategy decisions
    • Monitor external landscape, with a focus on close competitors, and keep track of the development of competitive assets and identify potential competitive threat
  • Team Leadership and Coaching:
    • Lead and mentor a high-performing business development and commercial assessment team
    • Foster a collaborative and results-driven culture
    • Provide guidance on deal structuring, relationship building, and strategic decision-making
  • External Communications:
    • Create compelling partner pitch decks that showcase SystImmune’s story and product portfolio. Collaborate closely with the scientific team to define and deliver key data packages for effective business development outreach
    • Build and maintain a network of business development professionals across the pharmaceutical and biopharma industries
    • Attend conferences, industry events, and investor meetings
  • Organizational System Development:
    • Establish an internal BD organizational system:
    • Track and document all collaborations along the BD pipeline
    • Provide regular status reports to senior leadership
Qualifications

Education: Advanced degree in life sciences required, with Ph.D. or M.D. preferred

Experience:

  • Minimum of 10 years in business development within the biopharmaceutical industry, search & evaluation experience preferred
  • Deep scientific understanding of a range of modalities of cancer therapeutics required
  • Proven track record of successful deal-making, including licensing, partnerships, and collaborations
  • Experience managing and coaching teams

Core Skills:

  • Strategic thinker with a deep understanding of drug development and commercialization
  • Excellent negotiation, communication, and presentation skills
  • Ability to balance scientific rigor with business acumen

Interpersonal competency:

  • Having a mindset of adaptability, curiosity, collaboration, resilience, and a passion for purpose is critical
  • Strong communication skills with effective problem-solving abilities

Compensation and Benefits:

The expected base salary range for this position is $280,000 - $380,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s qualifications, experience, and skills.

While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.

SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.

We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.

SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.

Salary : $280,000 - $380,000

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