Oligonucleotide Molecular Biology

Headquartered in Morrisville, NC, Synoligo Biotechnologies is a Contract Research Organization (CRO) focused solely on the research, development, and manufacturing of diagnostic and therapeutic oligonucleotides. We provide fast, one-stop services with high-end preclinical solutions and CMC consultancy. We help our customers navigate any CMC issue they may encounter, whether it’s starting raw materials or final product manufacturing for clinical trials. At Synoligo, we pride ourselves on being trusted partners in the discovery and development of life changing drugs. Join our team and help move science forward!

As an Oligonucleotide Molecular Biologist, you will be working alongside a small team of highly motivated scientists. Responsible for oligonucleotide assay development and screening, you will help influence the advancements of science, your career, and a growing biotechnology start-up.

What you'll do in this role

· Develop and execute in vitro cell based assay for RNA therapeutics screening of potency, off-target, cytotoxicity, etc. to support customers’ discovery programs

· Perform mRNA/cirRNA synthesis, purification and characterization.

· Support internal instrument validation, assay development and optimization and SOPs establishment

· Optimize and streamline in-house screening process with automation/liquid handler and data management process

· Analyze assay datasets and report data in a timely manner

· Support Biology lab reagent stock, equipment maintenance and consumables management

What you bring to the table

· B.S./M.S. in Cellular Biology, Molecular Biology, Pharmaceutical Sciences or related field.

· 1-3 year’s relevant experience in biotechnology and/or pharmaceutical industry with demonstrated accomplishments.

· Hands-on experience with qPCR, digital PCR, luciferase reporter assay, RNA/DNA extraction, mRNA, IVT is required.

· A track record of working on mammalian, primary and iPSC cell lines culture, transfection, electroporation, etc. is required.

· Experience with developing high-throughput assay with automation is highly preferred.

· Excellent communications, organization, and time management skills and ability to work both independently and collaboratively.

What we offer you

· Competitive Compensation

· Medical, Dental and Vision Insurance

· 401k with Company Match

· Paid Time Off (PTO)

· Flexible work schedule

· The opportunity to help build a department, influence policy and be a part of a team doing impactful work!

Job Type: Full-time

Benefits:

• 401(k)
• 401(k) matching
• Dental insurance
• Flexible schedule
• Flexible spending account
• Health insurance
• Health savings account
• Life insurance
• Paid time off
• Vision insurance

Work Location: In person