What are the responsibilities and job description for the Immunology & Protein Degradation Scientist position at Synectics Inc.?
Description
Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics.
Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.
Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first enrollment date that is at least 30 days after employment begins. Enrollment dates are each January 1st, April 1st, July 1st, and October 1st.
Technical Certification Bonus: Synectics is pleased to award its employees a bonus of up to $500 for an approved professional certification. In determining the bonus amount, Synectics will consider the cost of the test(s) for any certification relating to your current position, achieved during your employment with us. Only one Certification Bonus per calendar year may be awarded per employee. Only current, active employees will be eligible to receive this bonus. It will be awarded 90 days after the Synectics office has received documentation confirming the successful completion of the certification.
Synectics is an equal opportunity employer.
- We are currently seeking a highly motivated and passionate scientist to join the Exploratory Biologics group within the Immunology Discovery Department in Cambridge, MA.
- The successful candidate will contribute to the discovery of targeted therapeutic molecules by evaluating novel protein degraders through functional cellular assays, leveraging strong expertise in cell biology and biochemistry.
- This position provides an exciting opportunity for a talented scientist to grow their career in a dynamic, innovative, and multi-disciplinary environment at the interface of basic research and early drug discovery.
- The scientist will be responsible for conceptualizing, designing, and executing experiments, generating and characterizing therapeutic reagents, and conducting data analysis to advance innovative drug discovery programs.
- Bachelor's or Master's degree in Immunology, Cell Biology or a related Biological Sciences field, with 3-5 years of relevant hands-on experience.
- Extensive experience in in vitro human cell culture, including various immune cell types, with proven ability in cell-based assay development.
- Proficiency in multi-color flow cytometry, including instrument operation (e.g., BD Canto, MACSQuant) and independent data analysis using FlowJo or equivalent software.
- Strong background in cell biology and biochemistry techniques, such as ELISA/MSD, Western blotting, Wes/Jess, and confocal microscopy.
- Demonstrated ability to design, plan, and execute well-controlled in vitro experiments using novel research tools or reagents.
- Hands-on experience with protein-protein interactions, degradation pathways and lysosomal biology is highly desirable.
- Prior research experience with cutting-edge protein degradation technologies (e.g., PROTACs, LYTACs, or related modalities) is strongly preferred.
- Self-motivated, detail-oriented, and able to work both independently and collaboratively in a dynamic research environment.
- Independent and collaborative, with excellent technical, written and oral communication skills, and a strong drive to contribute to breakthrough research in immunology and biologics.
Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics.
Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.
Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first enrollment date that is at least 30 days after employment begins. Enrollment dates are each January 1st, April 1st, July 1st, and October 1st.
Technical Certification Bonus: Synectics is pleased to award its employees a bonus of up to $500 for an approved professional certification. In determining the bonus amount, Synectics will consider the cost of the test(s) for any certification relating to your current position, achieved during your employment with us. Only one Certification Bonus per calendar year may be awarded per employee. Only current, active employees will be eligible to receive this bonus. It will be awarded 90 days after the Synectics office has received documentation confirming the successful completion of the certification.
Synectics is an equal opportunity employer.
