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Associate Scientist, Downstream Process Development

Sutro Biopharma
South San Francisco, CA Full Time
POSTED ON 9/8/2024 CLOSED ON 12/12/2024

What are the responsibilities and job description for the Associate Scientist, Downstream Process Development position at Sutro Biopharma?

Sutro Biopharma, Inc. is looking for an Associate Scientist to join the Downstream Process Development team. You will be working in a dynamic team environment to maximize our technology in a collaborative fast-paced environment.

Responsibilities: 
  • Design and independently execute experiments to develop efficient, effective downstream purification processes for antibodies and antibody-drug conjugates.
  • Applies engineering principles, scientific knowledge, and critical thinking to identify problems and develop solutions.
  • Participate in the transfer of downstream processes to Sutro’s manufacturing site, CMOs, and/or partner sites
  • Participate on cross-functional teams and the development and implementation of new technology.
  • Prepare technical reports and presentations to communicate experimental outcomes to internal teams and senior management
  • Present information and data in both written and verbal form
  • Documents experimental and process data.
  • Contributes to a clean, organized and safe working environment.
 
Qualifications: 
  • BS/ MS with 5-10 years or PhD with 1-5 years of industry experience, Chemical Engineering, Bioengineering, Biochemistry, or related discipline.
  • Biopharmaceutical industry experience in protein purification (multiple modes of chromatography, depth & membrane filtration & ultrafiltration/TFF). Knowledge of product variant and process-related impurity removal strategies expected. Chromatography experience preferred.
  • Familiarity with routine in-process analytics to support process development (eg. Protein concentration, HPLC, endotoxin, ELISA).
  • Experience in transferring and supporting purification processes from bench scale to pilot and/or commercial scale. Understanding of working in GMP environments.  
  • Experience with statistical design of experiments, advanced data analysis, process validation and Quality by Design concepts.
  • Experience with protein conjugation process chemistry and formulation is preferred, but not required.
  • Strong ability in execution and driving for results independently.
  • Detail oriented with good organizational skills and able to work in a high paced team environment to meet deadlines and prioritize work on multiple projects.
  • Excellent communication skills, both verbal and written, and the ability to build and maintain relationships with team members, partners, customers, and collaborators.   

    Sound exciting? Apply today and join our team! 
    Sutro Biopharma, Inc. encourages all colleagues to be fully vaccinated for COVID-19 prior to the first date of employment.  

    As an equal-opportunity employer, we believe in fostering a culture that is inclusive and values diversity in background and opinions. Sutro Biopharma hires extraordinary individuals into every position in the company and is committed to the diversity of our team. Our company progresses without regard to race, ethnicity, gender, sexual orientation, religious belief, age, disability or citizenship status. We are dedicated to creating a safe environment where our employees can grow and succeed together.
     
    We look forward to hearing from candidates who are interested in exploring opportunities with Sutro! Our People & Culture team/hiring managers are unable to respond and do not accept solicitations from third-party agencies. 
      
    The anticipated salary range for fully qualified candidates applying for this role at Sutro Biopharma’s California-based locations will be $120,000 – $140,000  (not including bonus, equity, and benefits). The final salary offered will be dependent on several factors that include and are not limited to relevant previous experience, job responsibilities and duration of experience, the type and length of experience within the industry, and education.     
     
    About Sutro Biopharma     
     
    Sutro Biopharma, Inc., is a clinical-stage company relentlessly focused on the discovery and development of precisely designed cancer therapeutics, transforming what science can do for patients. Sutro’s fit-for-purpose technology, including cell-free XpressCF®, provides the opportunity for broader patient benefit and an improved patient experience. Sutro has multiple clinical stage candidates, including luveltamab tazevibulin, or luvelta, a registrational-stage folate receptor alpha (FRα)-targeting ADC in clinical studies. A robust pipeline, coupled with high-value collaborations and industry partnerships, validates our continuous product innovation. Sutro is headquartered in South San Francisco. For more information, follow Sutro on social media @Sutrobio, or visit www.sutrobio.com.   
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