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Executive Director, Commercial Operations

summittherapeutics
Princeton, NJ Full Time
POSTED ON 7/7/2026
AVAILABLE BEFORE 9/7/2026

About Summit:

Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people. Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence.

Summit’s team is inspired to touch and help change lives through Summit’s clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies, including:

Non-small Cell Lung Cancer (NSCLC)

  • HARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI.

  • HARMONi-3: Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.

  • HARMONi-7: Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC.

Colorectal Cancer (CRC)

  • HARMONi-GI3: Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy.

Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.


Overview of Role:

The Executive Director Commercial Operations will play a pivotal role in driving the success of our commercial strategies and ensuring operational excellence. You will lead a team responsible for various aspects of commercial operations including sales operations marketing operations meetings and events and project management. This role will report into the Head of US Commercial.

 

Role and Responsibilities:

  • In partnership with senior leadership develop and execute commercial strategies that align with the company's overall objectives.
  • Lead and coordinate sales operations marketing operations meetings and conventions and commercial project management.
  • Translate strategic initiatives into actionable plans for the commercial operations team.
  • Oversee the collection analysis and interpretation of sales data to inform decision-making processes.
  • Provide insights to optimize sales performance and resource allocation.
  • Develop and execute strategies for sales operations including CRM systems territory planning and incentive compensation.
  • Oversee MLR reviews promotional materials and campaign execution.
  • Manage meeting logistics contract negotiations and event registration.
  • Create and oversee integrated launch project plans facilitate cross-functional meetings and monitor progress.
  • Develop and implement strategies to maximize the productivity and efficiency of the sales force.
  • Evaluate and optimize sales territories compensation plans and incentive programs.
  • Ensure compliance with regulatory requirements and quality standards in distribution processes.
  • All other duties as assigned

 


Experience, Education and Specialized Knowledge and Skills:

  • Bachelor's degree in Business Administration Marketing or related field; MBA or advanced degree preferred
  • A minimum of 15 years of experience across multiple departments within commercial operations within the pharmaceutical or biotechnology industry with a track record of success in strategic planning and execution
  • Minimum of 5 years of experience in oncology is required
  • Strong analytical skills and ability to translate data into actionable insights
  • Excellent leadership and communication skills with the ability to effectively collaborate across functions and influence stakeholders at all levels
  • In-depth knowledge of pharmaceutical sales processes market dynamics and regulatory environment
  • Ability to thrive in a fast-paced dynamic environment and adapt to changing priorities

 

 

This is the pay for this position

Pay Transparency

$245,000 - $300,000 USD

 

Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.

Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at recruiting@smmttx.com to obtain prior written authorization before referring any candidates to Summit.

Summit Therapeutics Inc. is an Equal Opportunity Employer and takes pride in creating and maintaining diverse environment. We do not discriminate in recruitment, hiring, training or promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.

Salary : $245,000

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