Demo

Head of AI

Subsense Inc.
Palo Alto, CA Full Time
POSTED ON 4/4/2026
AVAILABLE BEFORE 9/29/2026
The Opportunity
We’re looking for a Head of AI to build and lead our AI-driven discovery platform — from virtual material generation to closed-loop validation with experimental data.

You will define how AI becomes a core engine of Subsense: generating novel nanoparticle designs, guiding synthesis, accelerating IP creation, and enabling a scalable, automated discovery pipeline.

This is a rare opportunity to own AI at the core of a new scientific paradigm.

We’re looking for someone who doesn’t wait for direction, but proactively explores the frontier where biotech meets AI. Someone who gets their hands dirty experimenting with what’s possible.

You believe generative AI can dramatically accelerate and transform the way biotech labs operate—and you’re excited to push that belief into reality with the right team and resources, by building and testing things that have never been done before.

Key Responsibilities


  • Build and lead the AI platform from scratchfor:
    • virtual generation of novel biocompatible magnetic nanoparticles
    • synthesis guidance and optimization
    • prediction of biological and physical properties
    • Integrate experimental data into model fine-tuning loops (CRO in-house)

  • Partner with leading AI companies to accelerate and enhance our biotech development
  • Drive creation of new IP through AI-generated materials, compositions, and model frameworks
  • Partner closely with R&D to translate AI outputs into real-world synthesis and validation
  • Establish a scalable pipeline:
    • generate → prioritize → synthesize → test → learn → iterate
    • Lead transition from outsourced validation (CROs) to partially in-house AI-guided experimentation
    • Define and implement data infrastructure, datasets, and feedback loops
    • Build toward full-stack automation of discovery (early stage)
    • Hire and lead a high-performance AI / ML team over time



    What You'll Bring
    Must-have experience
  • 8 years in AI / ML, with strong focus on applied scientific or deep-tech problems
  • Experience building and deploying ML models in:
    • materials science, chemistry, biology, or physics (preferred)
    • or other complex, data-sparse domains

  • Proven track record of:
    • turning models into real-world outcomes
    • working with experimental or noisy datasets

  • Strong experience with:
    • generative models / optimization systems
    • simulation-informed ML or hybrid modeling approaches
    • data pipelines and iterative learning systems

  • Ability to work closely with experimental scientific teams
  • Experience leading or mentoring technical teams


Strong plus


  • Background in:
    • materials discovery / computational chemistry
    • nanoparticle research
    • bio/chem ML or physics-informed ML

  • Experience building AI platforms (not just models)
  • Startup or zero-to-one environment experience
  • IP generation/patent exposure


We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

Salary.com Estimation for Head of AI in Palo Alto, CA
$167,447 to $215,003
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