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Genomic Sequencing Technologist (Laboratory Technologist II)-61111128

State of South Carolina
Richland, SC Full Time
POSTED ON 4/17/2026
AVAILABLE BEFORE 4/29/2026


Careers at DPH: Work that makes a difference!

Embracing Service, Inspiring Innovation, Promoting Teamwork, Pursuing Excellence, and Advancing Equity


Under the supervision of the Advanced Molecular Detection Supervisor, the technologist performs advanced Molecular laboratory procedures for outbreak detection and identification including of existing and emerging Public Health pathogens of interest, utilizing Whole Genome Sequencing (WGS), Next-Generation Sequencing (NGS), and Norovirus amplification, purification and sequencing protocols. 

Perform Whole Genome Sequencing (WGS) testing on microbial isolates (including but not limited to Salmonella, Carbapenem-Resistant Organisms (CRO)Shiga Toxin-producing E.coli (STEC), Campylobacter, Vibrio and Listeria). Operates and maintains equipment, as well as maintaining up-to date records of instrument and equipment maintenance and function verification checks. Perform molecular testing for Norovirus including conventional and Real-time Polymerase Chain Reaction (PCR), sample purification and sequencing analysis. Must maintain time and volume requirements for WGS and Norovirus testing as directed by grants.

Perform Next-Generation Sequencing on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Influenza, and other viral and bacterial specimens as protocols are introduced.

Must maintain Centers for Disease Control and Prevention (CDC) WGS and Norovirus sequencing certifications through PulseNet and CalicNet for test performance and perform necessary Quality Assurance (QA) and Quality Control (QC) activities. QA and QC records must be kept up-to date and maintained for accuracy to document compliance with laboratory regulatory and accreditation agencies’ guidelines, standards, and regulations. Continuously exhibit excellent communication and written skills of technical information to state SC DPH, epidemiological counterparts, CDC, and U.S. Food and Drug Administration (FDA).

Must maintain up-to date records of all supplies and reagents that are used for testing, as well as maintaining adequate supply amounts at all times.

State Minimum Requirements: A bachelor's degree in a related medical or scientific discipline; or an associate degree or equivalent training in a related medical, scientific or technical discipline and journey-level work experience in a related field.

Institutions of Higher Learning must be recognized by the Council for Higher Education Accreditation.

Agency Additional Requirements: Applicants indicating college credit or degree(s) on the application may upload an unofficial copy of the transcript as an attachment to the application. Please note that the agency will require an official, certified copy of the transcript or diploma prior to hiring.

Any equivalent combination of education and/or experience that demonstrates the required knowledge, skills, and abilities may be considered in meeting the minimum qualifications, subject to approval by the DPH Chief Human Resources Officer, or their delegate.

Experience with Molecular techniques and methods (i.e., genomic extraction, Real-Time Reverse Transcription-Polymerase Chain Reaction (RT-PCR), Mass Spectrometry, etc.) is preferred. Experience related to genomic sequencing and or genomic data analysis is preferred.

EEO: The Department of Public Health is committed to providing equal employment opportunities to all applicants and does not discriminate on the basis of race, color, religion, sex (including pregnancy, childbirth, or related medical conditions including, but not limited, to lactation), national origin, age (40 or older), disability, or genetic information. 

REASONABLE ACCOMMODATION: Applicants needing accommodation for medical reasons or a sincerely held religious belief may submit a request for accommodation.  A reasonable accommodation may be granted if it doesn't impose an undue hardship or pose a direct threat to the health and safety of others. 

STATE DISASTER PLAN: In accordance with the State's Disaster Plan, which includes hazardous weather, Department of Public Health employees may be required to work in times of an emergency or disaster. 

DRIVING RECORD: If this position requires the applicant to possess a valid driver's license to operate a state vehicle or personal vehicle, any applicant, being considered in the final stages of selection for the position will be required to provide a certified copy of a 10-year driving record.

The South Carolina Department of Public Health offers an exceptional benefits package for Full Time Employees (FTE) positions that includes:

  • 15 days Annual (Vacation) Leave per year
  • 15 days Sick Leave per year
  • 13 Paid Holidays
  • Paid Parental Leave
  • Health, dental, vision, long-term disability, and life insurance for employees, spouse, and children. Click here for additional information.
  • S.C. Deferred Compensation Program available (S.C. Deferred Compensation)
  • Retirement benefit choices *
    • State Retirement Plan (SCRS)
    • State Optional Retirement Program (State ORP)

*Enrollment in one of the listed plans is required for all Full Time Employees (FTE); please refer to the contribution section of hyperlinked retirement sites for the current contribution rate of gross pay.

HYBRID WORK: The option to work partially remote or adjusted work hours may be available after 12 months of employment for approved positions.

Salary : $52,100 - $54,000

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