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Research Associate/Associate Scientist, Assay Development

Spear Bio
Woburn, MA Full Time
POSTED ON 12/30/2025
AVAILABLE BEFORE 2/5/2026
Spear Bio, founded in 2021, is a well-funded and rapidly growing biotech start-up headquartered in Woburn, Massachusetts. Our proprietary technology, Successive Proximity Extension Amplification Reaction (SPEAR), is a novel wash-free immunoassay platform, offering unprecedented sensitivity. We are dedicated to revolutionizing early disease diagnosis and monitoring by providing scalable, ultrasensitive solutions that deliver unparalleled accuracy in measuring low-abundant biomarkers, enabling clinicians and researchers to improve patient outcomes and advance global health.

Research Associate/Associate Scientist

We are seeking a highly motivated and experienced Research Associate/Associate Scientist to join our growing Assay Development team, with hands-on experience running ultrasensitive immunoassays and the desire to be at the forefront of innovative research. This individual will play a pivotal role in advancing Spear Bio’s new range of ultrasensitive immunoassays and assay biomarker programs.

This role is based onsite in our lab in Woburn, MA 5 days/wk.

Responsibilities

  • Test and execute immunoassay workflows on high-throughput, semi-automated platforms
  • Assist in optimizing methods for processing different types of biofluid samples (ie. serum, plasma) for assay development
  • Set up, calibrate, and maintain laboratory equipment, as specified by the requirements of various projects
  • Assist in data analysis
  • Acquire necessary equipment and supplies for various projects

Qualifications

  • Master's degree in Biology, Biochemistry, Biophysics, Biomedical Engineering or a related discipline plus 1-3 years of assay development experience in an industry or academic lab
  • Direct experience running biofluid-based immunoassays and qPCR experimentation is required
  • Experience with neurodegenerative disease protein biomarkers a plus (ie. pTau217, pTau181, NFL, GFAP, alpha-synuclein, etc.)
  • Experience characterizing and troubleshooting immunoassays
  • Strong proficiency in molecular biology lab techniques

General Qualifications

  • Self-motivated and ability to perform complex tasks in an effective manner
  • Ability to follow instructions and grow in a mentorship setting
  • Excellent organizational and documentation skills
  • Desire to learn and implement new technologies
  • Strong presentation and interpersonal skills, ability to build collaborative working relationships, and become a key contributor within the assay development team
  • Work 5 days/week on site in Woburn, MA. LOCAL CANDIDATES will be given priority consideration for this position.

We offer competitive compensation, meaningful stock ownership, comprehensive benefits, and a great work environment. This is an opportunity to enter an innovative, high-growth startup at an early stage and play an integral role in the company's growth and success. We are focused on identifying candidates who have demonstrated leadership and excellence throughout their careers and are excited by the prospect of building an industry-leading company.

Spear Bio Inc. provides equal opportunity in employment to all persons. No person shall be denied equal access because of race, creed, color, religion, national origin, sex, sexual orientation, gender identity, age, or physical/mental disability.

Spear Bio does not accept resume submissions from external recruiting agencies. Any unsolicited resumes or candidate information submitted without prior written agreement will be deemed the property of Spear Bio, and no placement fees will be paid.

Compensation Range: $80K - $90K

Salary : $80,000 - $90,000

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