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Associate Scientist/Senior Associate Scientist, Assay Development

Spear Bio
Woburn, MA Full Time
POSTED ON 12/5/2025 CLOSED ON 1/5/2026

What are the responsibilities and job description for the Associate Scientist/Senior Associate Scientist, Assay Development position at Spear Bio?

Spear Bio, founded in 2021, is a well-funded and rapidly growing biotech start-up headquartered in Woburn, Massachusetts. Our proprietary technology, Successive Proximity Extension Amplification Reaction (SPEAR), is a novel wash-free immunoassay platform, offering unprecedented sensitivity. We are dedicated to revolutionizing early disease diagnosis and monitoring by providing scalable, ultrasensitive solutions that deliver unparalleled accuracy in measuring low-abundant biomarkers, enabling clinicians and researchers to improve patient outcomes and advance global health.

Associate Scientist/Senior Associate Scientist, Assay Development

We are seeking a highly motivated and experienced Associate Scientist/Senior Associate Scientist to join our Assay Development team, with hands-on experience in developing and validating ultrasensitive immunoassays.

The ideal candidate will support the full lifecycle of assay development, from initial concept and research to validation and assay transfer. This individual will play a pivotal role in advancing Spear Bio’s new range of ultrasensitive immunoassays and assay biomarker programs.

This role is based onsite in our lab in Woburn, MA 5 days/week.

Responsibilities

  • Design, develop, and optimize ultrasensitive immunoassays to support Spear Bio’s product pipeline.
  • Execute immunoassay workflows with a focus on high-throughput and semi-automated platforms.
  • Perform comprehensive troubleshooting to resolve technical challenges and improve assay performance.
  • Optimize methods for processing different types of clinical samples for assay development.
  • May serve as a technical lead for custom assay development projects and working directly with customers.

Requirements

  • BS in Biology, Biochemistry, Biomedical Engineering or a related discipline plus minimum of 2-3 years in an academic or industry lab; or MS degree plus 1-2 years of academic/industry lab experience.
  • Direct experience running immunoassays is required for consideration.
  • Hands-on experience utilizing ultrasensitive platforms like Simoa, MSD, Lumipulse, and/or homebrew platforms for novel immunoassay development preferred.
  • Previous experience with customer assay development is a plus
  • Experience characterizing and troubleshooting immunoassays
  • Strong proficiency in molecular biology lab techniques

General Qualifications

  • Self-motivated, with ability to perform complex tasks in an effective manner
  • Ability to follow instructions, learn, and grow in a mentorship setting
  • Excellent organizational and documentation skills
  • Desire to learn about and implement new technologies

We offer competitive compensation, meaningful stock ownership, comprehensive benefits, and a great work environment. This is an opportunity to enter an innovative, high-growth startup at an early stage and play an integral role in the company's growth and success. We are focused on identifying candidates who have demonstrated leadership and excellence throughout their careers and are excited by the prospect of building an industry-leading company.

Spear Bio Inc. provides equal opportunity in employment to all persons. No person shall be denied equal access because of race, creed, color, religion, national origin, sex, sexual orientation, gender identity, age, or physical/mental disability.

Spear Bio does not accept resume submissions from external recruiting agencies. Any unsolicited resumes or candidate information submitted without prior written agreement will be deemed the property of Spear Bio, and no placement fees will be paid.
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Salary.com Estimation for Associate Scientist/Senior Associate Scientist, Assay Development in Woburn, MA
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