Postdoctoral Fellowship in Human Synaptic Physiology

This is a traditional postdoctoral fellowship position that typically applies to neuroscientists within 5 years of receiving their PhD. The Anderson lab at CHOP/Penn uses human stem cell derived excitatory and inhibitory neurons, astrocytes, microglia, and neurovascular-like cells in mono-and mixed carpet cultures, as well as organoid differentiations, as tools for the study of gene-gene and gene-environment interactions in neuropsychiatric disease. Illnesses of particular interest include schizophrenia and autism, with emphasis on mitochondrial influences on symptom penetrance and treatment. For this position the focus is on live imaging of presynaptic vesicle cycling and glutamate release in human stem cell derived neurons from patients with autism and schizophrenia. To be considered applicants must have substantial experience in conducting whole cell electrophysiological recordings and/or live imaging of neuronal activity. Experience in human stem cell culture, manipulation, and differentiation is preferred but not required. Come study developmental and translational neuroscience with us!