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Senior Applied LLM Engineer

Simple Solutions
San Francisco, CA Full Time
POSTED ON 4/23/2026
AVAILABLE BEFORE 5/23/2026
Senior Applied LLM Engineer
San Francisco, CA, USA (Onsite)
Fulltime position
Qualifications:
  • Bachelor s or Master s degree in Computer Science, Engineering, or a related field (or equivalent practical experience)
  • 3 years of software development experience, with a focus on building and deploying AI/ML applications
  • Strong backend engineering experience, including:
    • Building APIs from the ground up using Python frameworks such as FastAPI and Django
    • Deploying and scaling containerized applications in cloud environments (e.g., AWS, Google Cloud Platform, Azure)
    • Implementing CI/CD pipelines (e.g., GitHub Actions)
    • Working with Infrastructure-as-Code tools such as Terraform or Pulumi
  • Hands-on experience building LLM-based applications, including:
    • Designing multi-step LLM workflows and task-specific agents
    • Experience working with most frontier models (e.g. OpenAI, Anthropic, Google, etc )
    • Experience with AI tools as a user, specifically AI code editors
    • Developing advanced prompt engineering strategies, evaluation frameworks, and RAG pipelines
    • Conducting technical R&D to explore and define the boundaries of model functionality
  • Familiarity with secure coding practices, ideally in regulated industries (e.g., life sciences, healthcare, fintech)
  • Experience working in or adjacent to regulated domains (life sciences, clinical R&D) is a plus
  • Frontend development experience (e.g., React) is a plus, but not required

Requirements:

  • Ability to design and maintain scalable, production-grade backend systems for AI applications
  • Ability to create, orchestrate, and evaluate LLM-based agents and chained workflows with minimal oversight
  • Ability to debug and improve LLM-driven systems, identifying issues across multiple layers (model output, API behavior, system logic)
  • Ability to conduct rapid experimentation and research on LLM capabilities and translate findings into production functionality
  • Ability to stay current with emerging practices, models, and tooling in the generative AI ecosystem and apply them pragmatically
  • Ability to communicate clearly with technical and non-technical collaborators (e.g., product managers, medical writers, customer teams)
  • Ability to operate effectively in a fast-paced, ambiguity-heavy environment, managing shifting priorities and novel problem spaces

Other Information:

  • Very comfortable working in a fast-paced and intense startup environment
  • Willing to work in-person in our office in Mission Bay 4-5 days/week
  • Likes matcha KitKats, believes every LLM prompt is just Schrodinger s cat waiting to be observed, and knows too many random facts about the Mongol postal system

Salary : $200,000

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