RA-II/SRA, Histology Technician

Rubedo Life Sciences is a clinical-stage biopharmaceutical company pioneering longevity medicines. Using our proprietary ALEMBIC™ drug discovery platform and SenTeCh™ chemistry, we develop therapies that selectively clear aging and diseased cells, senescent “zombie” cells, across multiple disease areas, including dermatology, pulmonology, neurodegeneration, fibrosis, oncology, and metabolic disorders.

Headquartered in Sunnyvale, CA, with offices in Milan, Italy, we are driven by a mission to transform health span and longevity through innovative science.

We are seeking a highly motivated and skilled researcher with previous knowledge of immunohistochemistry to contribute to preclinical and translational research, advancing the discovery of molecular targets and therapeutics for age-related pathobiologies. A successful candidate will have extensive experience with automated immunohistological techniques, excellent organizational and record keeping skills, the desire to learn new laboratory methods, and the ability to follow protocols with attention to detail.  The candidate will work closely with the in vivo pharmacology team, pathologists and image analysts.

Responsibilities:

• Sample accessioning, embedding, microtomy, cryotomy 
• Staining of chromogenic and immunofluorescent singleplex and multiplexing panels using an automated IHC platform 
• Imaging of stained slides with a whole slide scanner 
• Quality assessment of stained/scanned samples and controls 
• Creation of basic and/or complex experimental study designs 
• Communicate and present results to colleagues
• Maintain accurate tissue, slide, and lab records in an electronic notebook; document methods in SOPs and results in technical reports
• Clean and maintain instruments and work areas 
• Work closely with the histology team, in vivo pharmacology team, pathologists, and other researchers develop tailored histology solutions.
• Keep informed of the latest developments in histology and apply new techniques to improve existing workflows.

Qualifications:

• More than 3 years of histology experience or previous industry-related research experience
• Strong understanding and technical competence with immunohistochemistry techniques, antibody validation, assay development and immunofluorescent multiplexing   
• Previous experience with IHC automated staining platforms 
• Technical competence in basic histology 
• Knowledge of basic tissue histology/pathology
• Excellent record-keeping and organizational skills and attention to details
• Ability to organize and prioritize assigned tasks for completion within expected time-frames
• Excellent verbal and written communication skills
• Proficient with Google Workspace software or comparable software
• Preferred Histology Technician (HT) or Histotechnologist (HTL) certification
• Preferred experience with image analysis. 

Environmental Conditions / Physical Demands:

• 80% of time onsite conducting wet lab work 
• Prolonged periods of standing at laboratory tables
• Physical: Lifting up to 20 lbs occasionally, standing, bending, repetitive movement, etc.
• Environmental risks: Exposure to wet lab environment, blood borne pathogens, and toxic or caustic chemical or reagents
• Work location: Sunnyvale and Mountain View, CA, USA

Equal Opportunity Employer

Rubedo Life Sciences is an equal opportunity employer and is committed to building an inclusive and diverse workplace.