What are the responsibilities and job description for the Scientist II, Cheminformatics position at Relay Therapeutics?
The Opportunity:
Relay Therapeutics is seeking a highly motivated Scientist to join our Drug Discovery team in a unique hybrid role that integrates synthetic chemistry with cheminformatics. This position is ideal for a scientist who enjoys working at the interface of experimental and computational disciplines and is excited to help shape how data-driven chemistry is done in a modern biotech environment.
Your Role:
The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.
#BP1
About Relay Therapeutics
Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process.
Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you’re excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!
Relay Therapeutics is seeking a highly motivated Scientist to join our Drug Discovery team in a unique hybrid role that integrates synthetic chemistry with cheminformatics. This position is ideal for a scientist who enjoys working at the interface of experimental and computational disciplines and is excited to help shape how data-driven chemistry is done in a modern biotech environment.
Your Role:
- Maintain and support tools used in compound registration, lab operations and data ingestion from assays, as well as broader data and software access workflows
- Design and execute synthetic chemistry workflows, with a focus on high-throughput or parallel synthesis to support medicinal chemistry programs
- Contribute to the design, enumeration, and prioritization of compound libraries using cheminformatics tools
- Collaborate closely with computational chemists, data scientists, and medicinal chemists to guide compound design using data-driven insights
- Analyze and interpret experimental data to inform structure–activity relationships (SAR) and compound optimization
- Help develop and refine internal workflows that integrate synthetic chemistry with computational approaches
- Maintain clear documentation and communicate results effectively across multidisciplinary teams
- Ph.D. or M.S. in Organic Chemistry or a related field, with 2–5 years of relevant industry experience preferred
- Demonstrated experience in synthetic organic chemistry
- Familiarity with cheminformatics tools and concepts (e.g., molecular representations, library design, property prediction)
- Experience with scripting or data analysis tools (e.g., Python, RDKit)
- Strong problem-solving skills and the ability to work both independently and collaboratively
- Excellent communication skills and a desire to work in a highly cross-functional environment
- A scientist who enjoys bridging “hands-on” chemistry with computational thinking
- Someone comfortable working in a fast-paced, evolving biotech setting
- A candidate who is curious, adaptable, and interested in shaping new ways of integrating chemistry and data science
The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.
#BP1
About Relay Therapeutics
Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process.
Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you’re excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!
Salary : $88,000 - $126,000