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Research Scientist, DMPK

Recruits Lab
South San Francisco, CA Full Time
POSTED ON 10/22/2025 CLOSED ON 12/21/2025

What are the responsibilities and job description for the Research Scientist, DMPK position at Recruits Lab?

Research Scientist, DMPK (Contract)
📍 Location: South San Francisco, CA
đź’Ľ Contract Duration: 12 months

Overview
Our client, a leading precision medicine oncology company, is seeking a Research Scientist, DMPK with a strong background in analytical and bioanalytical chemistry to support in vitro and in vivo ADME studies.
The ideal candidate is an experienced, hands-on scientist skilled in cellular incubation, biological sample extraction, and LC-MS analysis. You’ll play a key role in characterizing drug metabolism and pharmacokinetics to accelerate the development of novel oncology therapeutics.
This role requires on-site presence four days per week at the South San Francisco location.

Key Responsibilities
  • Perform cellular uptake and metabolite profiling assays.
  • Conduct biological sample preparation and LC-MS analysis.
  • Process raw data, maintain accurate electronic lab notebook (ELN) records, and prepare study reports.
  • Contribute to bioanalytical method development and metabolite identification.
  • Identify and troubleshoot technical challenges, continuously improving analytical workflows.
  • Ensure compliance with company policies and standard operating procedures.
  • Maintain accurate records of samples, reagents, and experimental details.
  • Foster a collaborative and organized lab environment.

Qualifications
  • Education: B.S. or M.S. in Biology, Chemistry, Pharmaceutical Sciences, or a related discipline.
  • Experience: Minimum of 2 years of hands-on experience in industry or an academic laboratory.
  • Knowledge of ADME and drug metabolism principles.
  • Proficiency in cellular incubation and biological sample processing.
  • Experience with LC-MS and LC-UV quantification of drugs, metabolites, or xenobiotics.
  • Strong record-keeping and communication skills, with familiarity in maintaining ELN records.
  • Proficiency with software such as Word, Excel, PowerPoint, and GraphPad.
  • Experience with Sciex and Thermo mass spectrometers and related software (e.g., Analyst, Xcalibur) is highly desirable.

Additional Details
  • Type: Contractor (12 months)
  • Work Environment: On-site, four days per week (South San Francisco)

Salary.com Estimation for Research Scientist, DMPK in South San Francisco, CA
$126,226 to $156,265
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