What are the responsibilities and job description for the Scientist, Cell Biology position at RBL LLC?
Company Overview:
RBL LLC is a Houston-based company incubator with the mission to select, develop, and spin out intellectual property, aiming to drive innovative biotech ventures. RBL LLC’s team of industry-experienced company builders provides comprehensive services to startups, including lab and office space, financial, administrative, and business development support as well as clinical trial design, implementation, talent acquisition, and capital sourcing to help early-stage companies build a strong foundation for clinical success.
Job Summary:
We are seeking a highly motivated and innovative Cell Biology Scientist to join our growing team. The ideal candidate will have expertise in cellular biology, immunology, and/or bioengineering with hands-on experience developing and characterizing cell-based therapies. This role will contribute to the design, execution, and analysis of experiments to advance novel therapeutic programs from discovery through early-stage development.
Key Responsibilities:
- Design and execute laboratory experiments to develop and optimize cell therapy platforms.
- Perform cell culture, genetic modification, expansion, cryopreservation and functional characterization of cell lines.
- Develop assays for cell and cell/biomaterial combination characterization and process validation.
- Develop, implement, and document experimental protocols, ensuring data integrity and reproducibility following Good Documentation Procedures.
- Author and review technical reports, batch records, Standard Operating Procedures (SOPs), and regulatory documentation.
- Support technology transfer activities to internal manufacturing sites or external contract manufacturing organizations (CMOs/CDMOs).
- Collaborate closely with cross-functional teams to align development activities with project goals, timelines, and regulatory requirements.
- Troubleshoot process-related issues during development, scale-up, and manufacturing campaigns.
- Collaborate with cross-functional teams in research, process development, analytical sciences, regulatory, and clinical operations.
- Contribute to the development of scalable processes suitable for clinical and commercial manufacturing.
- Analyze, interpret, and present scientific data to internal teams and external collaborators.
- Author technical reports, study summaries, and contribute to regulatory filings as needed.
- Stay current with emerging technologies and advancements in the cell therapy field.
Qualifications:
- Ph.D. in Cell Biology, Immunology, Bioengineering, or a related field with 0–3 years of postdoctoral/industry experience; or M.S. with 4 years of relevant experience.
- Strong background in mammalian cell culture and aseptic technique.
- Hands-on experience with adherent and suspended cell lines.
- Familiarity with genetic engineering techniques (e.g., viral and non-viral transduction, electroporation).
- Direct experience with cryopreservation, recovery, and stability testing cell products.
- Proficiency in multiparameter flow cytometry and functional cellular assays.
- Excellent problem-solving skills, with ability to design and troubleshoot experiments independently.
- Strong communication and collaboration skills, with the ability to work in a fast-paced, team-oriented environment.
Preferred Skills:
- Experience with process development for cell therapy manufacturing, including scale-up and closed-system technologies.
- Knowledge of GMP principles and regulatory requirements for cell and gene therapy products.
- Proficiency in data analysis software and statistical methods.
- Experience contributing to IND-enabling studies or regulatory documentation.
- Works independently
- Team player
RBL LLC is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, sexual orientation, or gender identity), national origin, age, disability, genetic information, veteran status, or any other protected characteristic as defined by applicable laws. If you require reasonable accommodation during the application or hiring process, please contact hr@rbl-llc.com.
Job Type: Full-time
Work Location: In person