What are the responsibilities and job description for the Clinical Trial Manager position at Rapport Therapeutics?
When our people share why they joined Rapport and love it here, it comes down to three things: the science, the mission, and the team. At Rapport, we’re driven by a passion for developing precision neuromedicines with the potential for fewer side effects, enabling patients and their families to enjoy healthier, more fulfilling lives. And we’re doing this with extraordinary science and awesome people (affectionately called Rapptors).
Our innovative scientific platform is centered on Receptor Associate Proteins (RAPs). RAPs are a component of neuronal receptor complexes, which play a crucial role in regulating receptor assembly and function. This precision approach has the potential to revolutionize the development of small molecule therapies. We are excited about the potential of our lead program, RAP-219. Our first indication targets focal epilepsy with additional clinical trials for neuropathic pain and bipolar disorder.
The strength of Rapport comes from our Rapptors – who are united by our mission to improve patients lives. We bring the heart and hustle to advance our science forward, always staying true to our core values. We hope you’re as excited about this opportunity as we are!
Your Impact
In this role, you’ll work with our Clinical Operations Leads to help keep trials running smoothly across multiple indications. It’s a hands-on, high-impact role on a fun, driven team where you’ll grow fast and make a real difference.
Your Day-to-day
We get it. Compensation is an important part of your offer. You shouldn’t be surprised at the end of the recruiting process, and you should know that your offer is fair and equitable. How do we do this? We tell you about our hiring range now - we expect the hiring range for this role to be $140,000 to $160,000. Our actual offer will reflect a lot of factors including your relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, we also offer a pretty great benefits package. We don’t stop here - if you join Rapport, we go to the next level. We share our full salary ranges for every level across our company.
This role is based in Boston, located at 99 High St. We prioritize in person connection with our fellow Rapptors! Our team members come together onsite at our Boston office on Tuesday and Wednesday. In January 2026, this will shift to three days a week to create more opportunities for innovation, collaboration, and connection.
Rapport Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.
CCPA disclosure notice can be found here.
Our innovative scientific platform is centered on Receptor Associate Proteins (RAPs). RAPs are a component of neuronal receptor complexes, which play a crucial role in regulating receptor assembly and function. This precision approach has the potential to revolutionize the development of small molecule therapies. We are excited about the potential of our lead program, RAP-219. Our first indication targets focal epilepsy with additional clinical trials for neuropathic pain and bipolar disorder.
The strength of Rapport comes from our Rapptors – who are united by our mission to improve patients lives. We bring the heart and hustle to advance our science forward, always staying true to our core values. We hope you’re as excited about this opportunity as we are!
Your Impact
In this role, you’ll work with our Clinical Operations Leads to help keep trials running smoothly across multiple indications. It’s a hands-on, high-impact role on a fun, driven team where you’ll grow fast and make a real difference.
Your Day-to-day
- Provide support to the Clinical Operations Lead (COL) in the planning, execution, and oversight of clinical trials from study start-up to close-out
- Manage the tracking of timelines, deliverables, and study milestones across one or more trials
- Maintain and organize trial documentation (e.g., TMF/eTMF oversight, trackers, meeting minutes) ensuring that study documentation is in a continuous state of inspection readiness
- Collaborate with CROs, vendors, and internal teams to facilitate smooth trial execution
- Help prepare study tools, communication plans, and team presentations
- Contribute to inspection readiness activities and ensure compliance with GCP and SOPs
- Monitor and help resolve site or study-level issues escalated by the COL
- Coordinate internal team meetings and participate in cross-functional study meetings
- Proactively communicate study updates with key internal and external stakeholders
- Support the development, review and tracking of study-related documents (protocols, ICFs, investigative brochure, monitoring visit reports, etc.)
- Bachelor’s degree in life sciences or healthcare related field
- 5 years of clinical operations experience within the biotech or pharma industry required
- Solid understanding of GCP, ICH guidelines, and the clinical development process
- Experience with clinical trial management systems (CTMS), eTMF, and other operational tools
- Ability to multitask and flex across projects as priorities and deadlines shift
- Highly organized with excellent communication and interpersonal skills
- Strong attention to detail and ability to multitask in a dynamic, fast-paced setting
- A collaborative team player that takes initiative
- Every role has meaning. We’re determined to discover a better way for patients, and you’ll feel the passion from the start.
- We are driven to innovate. Exciting science that pushes boundaries and opens new possibilities.
- Your perspective matters. Stick your neck out, share your ideas – we work as a team.
- We have FUN. We hire smart, dedicated, down-to-earth people that you’ll enjoy spending time with.
- Leadership that CARES – about you, your growth development.
- We're bicoastal. Whether you're in the lab full-time in San Diego or taking advantage of a more hybrid work schedule in Boston – we make the most of our time together.
- Competitive benefits. Including unlimited PTO, a lifestyle spending account, commuting reimbursement, and much more!
- You get to be YOU! Show up as you are and make every day count.
We get it. Compensation is an important part of your offer. You shouldn’t be surprised at the end of the recruiting process, and you should know that your offer is fair and equitable. How do we do this? We tell you about our hiring range now - we expect the hiring range for this role to be $140,000 to $160,000. Our actual offer will reflect a lot of factors including your relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, we also offer a pretty great benefits package. We don’t stop here - if you join Rapport, we go to the next level. We share our full salary ranges for every level across our company.
This role is based in Boston, located at 99 High St. We prioritize in person connection with our fellow Rapptors! Our team members come together onsite at our Boston office on Tuesday and Wednesday. In January 2026, this will shift to three days a week to create more opportunities for innovation, collaboration, and connection.
Rapport Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.
CCPA disclosure notice can be found here.
Salary : $140,000 - $160,000