RCI-ABBV-31873 Formulation Scientist (Biologics/Protein Characterization/HPLC/Monoclonal Antibodies)

US-IL-Lake County

100% onsite

Day to day –

• Large initiative kicked off in the past year, collecting data of 1000 biologic compounds, day to day will be mostly in lab doing liquid handling, processing biologics.
• Collecting data on instruments, in the lab sample prep. 2nd portion data analysis.
• Sitting in on bi weekly meeting, talk about data.
• Within initiative, things in the future, planning and other experiments to support.

Years of experience/education and/or certifications required:

• 3-5 years of experience.
• Masters with 0 years of experience is ok.
• Okay to teach and guide them.
• Science background
• Stand out if they have research lab experience, undergrad or master’s research lab
• Any type of wet lab skill.
• HPLC, Liquid handling major plus.

What is a nice to have (but not required) regarding skills, requirements, experience, education, or certification?

• PHD overqualified.

Work Schedule (Define days,# of hours)/ Is Overtime offered or required? If yes, how many hours, what impact to scheduled working hours?

• OT not going to be offered.

Working hours – 9-5

Scientist II, Biologics Drug Product Development

• The core role of BCD is to deliver meaningful and actionable data to support the selection of candidate molecules to progress through the pipeline into later stages of development.
• The group applies high-throughput (HT) assays and leverages automation to enable screening on a wide range of biologics.
• We are currently undertaking a multi-year initiative to collect data on a diverse selection of molecules using these established HT screening assays and automation.

Key Responsibilities Include:

• Sample preparation, data collection, and data analysis on established HT screening assays.
• Method development and execution of novel HT assays.
• Maintain an electronic lab notebook in alignment with company documentation policies.
• Stay current with scientific literature and support new scientific initiatives.

Qualifications

• BS or MS in a scientific field and typically 4 (BS) or 2 (MS) years of relevant experience.
• Hands-on experience using analytical methods for chemical and structural characterization of biologics e.g. HPLC/UPLC, capillary electrophoresis, and other biophysical techniques (UV-vis, DLS, DSF, etc.) for protein characterization is a requirement.
• Scientific understanding of the structure & function of monoclonal antibodies, antibody constructs/conjugates, bispecifics, and fusion proteins and their modes of degradation/stabilization.
• Strong laboratory skills focused on formulation development for monoclonal antibodies and antibody constructs/conjugates (standard excipient selection, functional excipients, high throughput assays).
• Desired: Experience with digital data capture tools and systems