What are the responsibilities and job description for the RASyn - Scientist, Protein Engineering position at RA Ventures?
About RASyn:
RASyn, a new biotechnology company launched by RA Capital, is building a proprietary platform of innovative technologies to transform the discovery and development of breakthrough therapeutic, diagnostic, and industrial products. RASyn’s platform integrates computational protein design and engineering, machine learning, synthetic biology, and single cell sequencing and will enable cheaper, faster, and larger scale production and optimization of biologics, enzymes, and biomolecule libraries. We are assembling a diverse team of the most talented scientists and innovators who seek to invent the future today and have a passion for solving the most intractable problems.
About RA Capital:
RA Capital funds and builds healthcare and life science companies using an evidence-based investment approach informed by TechAtlas, a think tank within RA Capital which analyzes scientific and clinical data from academic literature and industry sources to anticipate how breakthroughs might impact industry stakeholders, physicians, patients, and policymakers. TechAtlas' analyses are captured in a unique collection of competitive landscapes, or ‘maps’, which identify competitive therapeutics, diagnostics, research tools, and/or technological capabilities in a given area.
About the Role:
RASyn is seeking an innovative, self-motivated, and team-oriented Scientist in Protein Engineering, with a passion for developing assays to support the interrogation of protein libraries using a variety of display, cellular, and molecular techniques. In your role, you will support the team by executing, analyzing and presenting experiments to drive platform activities and improvements. You will work closely with our cross-functional teams and be a contributor supporting our R&D programs. As a member of a growing and engaged team, you will have the opportunity to take part in leading innovative research and development, and work with a highly skilled multidisciplinary team in a fast-paced startup environment.
Key Responsibilities:
RASyn, a new biotechnology company launched by RA Capital, is building a proprietary platform of innovative technologies to transform the discovery and development of breakthrough therapeutic, diagnostic, and industrial products. RASyn’s platform integrates computational protein design and engineering, machine learning, synthetic biology, and single cell sequencing and will enable cheaper, faster, and larger scale production and optimization of biologics, enzymes, and biomolecule libraries. We are assembling a diverse team of the most talented scientists and innovators who seek to invent the future today and have a passion for solving the most intractable problems.
About RA Capital:
RA Capital funds and builds healthcare and life science companies using an evidence-based investment approach informed by TechAtlas, a think tank within RA Capital which analyzes scientific and clinical data from academic literature and industry sources to anticipate how breakthroughs might impact industry stakeholders, physicians, patients, and policymakers. TechAtlas' analyses are captured in a unique collection of competitive landscapes, or ‘maps’, which identify competitive therapeutics, diagnostics, research tools, and/or technological capabilities in a given area.
About the Role:
RASyn is seeking an innovative, self-motivated, and team-oriented Scientist in Protein Engineering, with a passion for developing assays to support the interrogation of protein libraries using a variety of display, cellular, and molecular techniques. In your role, you will support the team by executing, analyzing and presenting experiments to drive platform activities and improvements. You will work closely with our cross-functional teams and be a contributor supporting our R&D programs. As a member of a growing and engaged team, you will have the opportunity to take part in leading innovative research and development, and work with a highly skilled multidisciplinary team in a fast-paced startup environment.
Key Responsibilities:
- Design, construct, and validate protein variant libraries using display techniques for platform activities,
- Develop novel constructs and assays to explore diverse functionalities using cellular and molecular methods,
- Leverage NGS and single cell technologies to interrogate libraries and single cell assays,
- Conduct and support biomolecular experiments with high precision and reliability,
- Contribute to projects through data generation, analysis, interpretation, and presentation,
- Maintain detailed electronic lab notebook and registration of constructs and biologics, and
- Follow Standard Operating Protocols and generate new ones when necessary.
Qualifications & Skills:
- A PhD in Biochemistry, Biological/Chemical Engineering, Microbiology, Biology or a Master’s degree in a related field with 3 years of laboratory experience,
- Expertise in mammalian cell culture, flow cytometry, FACS sorting, protein characterization and protein display technologies,
- Proficient in common molecular cloning techniques and sequencing (E.g., DNA/RNA isolation, PCR, qPCR, NGS library generation),
- Some background in immunology is preferred,
- Strong analytical skills, detail-oriented, and thrives in a fast-paced startup environment,
- Excellent communication skills (written and verbal) and adept at building strong relationships across teams,
- Highly adaptable, able to work both independently and collaboratively, and
- Self-motivated, proactive, and collaborative approach; driven to achieve scientific and business objectives.